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Beta-bloquants et obstruction bronchique: un si mauvais menage ?

Bria, A
Published in Revue médicale suisse. 2006, vol. 2, no. 50, p. 285-8
Abstract Chronic obstructive pulmonary disease is a frequent medical condition, mainly triggered by smoking. COPD patients often suffer from heart diseases that can benefit from beta-blocker therapy. However, fear from triggering latent bronchospasm, or from worsening it, leads to under-prescription of these agents. Adequate patient selection is, thus, crucial. Prescription of a cardio-selective beta-blocker is not only reasonably safe in stable COPD patients but it is also beneficial in terms of mortality in those patients with comorbid cardiac diseases. Use of beta-blockers is contra-indicated in the case of decompensated COPD with severe bronchospasm or in poorly controlled asthma. In all cases, close clinical and, sometimes, functional monitoring is mandatory.
Keywords Adrenergic beta-Antagonists/administration & dosage/adverse effects/contraindicationsBronchial Spasm/chemically inducedForced Expiratory VolumeHeart Diseases/complications/drug therapy/mortalityHumansPatient SelectionPulmonary Disease, Chronic Obstructive/complications/physiopathologyRandomized Controlled Trials as TopicSurvival Analysis
PMID: 16503045
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Research groups Groupe Perrier Arnaud (Médecine interne générale, de réhabilitation et de gériatrie) (585)
Groupe Jean-Michel Gaspoz (23)
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GROSGURIN, Olivier, BRIA, A, GASPOZ, Jean-Michel. Beta-bloquants et obstruction bronchique: un si mauvais menage ?. In: Revue médicale suisse, 2006, vol. 2, n° 50, p. 285-8. https://archive-ouverte.unige.ch/unige:34064

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Deposited on : 2014-02-04

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