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Origin of minority drug-resistant HIV-1 variants in primary HIV-1 infection

Metzner, Karin J
Scherrer, Alexandra U
Preiswerk, Benjamin
Joos, Beda
von Wyl, Viktor
Leemann, Christine
Rieder, Philip
Braun, Dominique
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Published in The Journal of Infectious Diseases. 2013, vol. 208, no. 7, p. 1102-12
Abstract Drug-resistant human immunodeficiency virus type 1 (HIV-1) minority variants (MVs) are present in some antiretroviral therapy (ART)-naive patients. They may result from de novo mutagenesis or transmission. To date, the latter has not been proven.
Keywords AdolescentAdultAgedAllelesCluster AnalysisCohort StudiesDrug Resistance, ViralFemaleGenetic VariationHIV Infections/transmission/virologyHIV-1/drug effects/genetics/isolation & purificationHumansMaleMiddle AgedPhylogenyPolymerase Chain ReactionSequence Analysis, DNASwitzerlandYoung Adult
PMID: 23847055
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Research group VIH/SIDA (930)
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METZNER, Karin J et al. Origin of minority drug-resistant HIV-1 variants in primary HIV-1 infection. In: The Journal of Infectious Diseases, 2013, vol. 208, n° 7, p. 1102-12. doi: 10.1093/infdis/jit310 https://archive-ouverte.unige.ch/unige:33946

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Deposited on : 2014-01-31

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