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Microalbuminuria and hyperfiltration in subjects with nephro-urological disorders

Cachat, Francois
Chehade, Hassib
Zeier, Gregory
Mosig, Dolores
Meyrat, Blaise
Frey, Peter
Published in Nephrology, Dialysis, Transplantation. 2013, vol. 28, no. 2, p. 386-91
Abstract Microalbuminuria (MA) has been shown to be an early biomarker of renal damage. It is postulated that MA is the early result of hyperfiltration, which could evolve into glomerular sclerosis and renal failure if hyperfiltration is left untreated. We hypothesized that MA is a good indicator of hyperfiltration in children with kidney disorders, obviating the need to calculate the filtration fraction (FF).
Keywords AdolescentAlbuminuria/physiopathology/urineBiological Markers/urineChildCreatinine/urineFemaleGlomerular Filtration Rate/physiologyHumansKidney/physiopathologyKidney Diseases/physiopathology/urineMaleMultivariate AnalysisPredictive Value of TestsProspective StudiesUrethral Obstruction/physiopathology/urineVesico-Ureteral Reflux/physiopathology/urine
PMID: 23223226
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Other version: http://ndt.oxfordjournals.org/content/28/2/386.long
Research groups Epidémiologie clinique (115)
Pathogénèse du syndrome néphrotique idiopathique de l'enfant (180)
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CACHAT, Francois et al. Microalbuminuria and hyperfiltration in subjects with nephro-urological disorders. In: Nephrology, Dialysis, Transplantation, 2013, vol. 28, n° 2, p. 386-91. doi: 10.1093/ndt/gfs494 https://archive-ouverte.unige.ch/unige:33944

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Deposited on : 2014-01-31

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