Sensitivity, specificity and likelihood ratios of PCR in the diagnosis of syphilis: a systematic review and meta-analysis

Gayet-Ageron, Angèle; Lautenschlager, Stephan; Bescher Ninet, Béatrice Alice; Perneger, Thomas; Combescure, Christophe

doi:10.1136/sextrans-2012-050622

Scientific article

Review

English

Sensitivity, specificity and likelihood ratios of PCR in the diagnosis of syphilis: a systematic review and meta-analysis

ContributorsGayet-Ageron, Angèle; Lautenschlager, Stephan; Bescher Ninet, Béatrice Alice; Perneger, Thomas; Combescure, Christophe

Published inSexually transmitted infections, vol. 89, no. 3, p. 251-256

Publication date2013

Abstract

To systematically review and estimate pooled sensitivity and specificity of the polymerase chain reaction (PCR) technique compared to recommended reference tests in the diagnosis of suspected syphilis at various stages and in various biological materials.

Keywords

Bacteriological Techniques/methods
Humans
Molecular Diagnostic Techniques/methods
Polymerase Chain Reaction/methods
Sensitivity and Specificity
Syphilis/diagnosis/microbiology
Treponema pallidum/genetics/isolation & purification

Affiliation

Faculté de médecine / Section de médecine clinique / Département de santé et médecine communautaires

Research group

Epidémiologie clinique (115)

Citation (ISO format)

GAYET-AGERON, Angèle et al. Sensitivity, specificity and likelihood ratios of PCR in the diagnosis of syphilis: a systematic review and meta-analysis. In: Sexually transmitted infections, 2013, vol. 89, n° 3, p. 251–256. doi: 10.1136/sextrans-2012-050622

Article (Published version)

Identifiers

PID : unige:33941
DOI : 10.1136/sextrans-2012-050622
PMID : 23024223

Commercial URLhttp://sti.bmj.com/content/89/3/251.long

ISSN of the journal1368-4973

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Sensitivity, specificity and likelihood ratios of PCR in the diagnosis of syphilis: a systematic review and meta-analysis

To systematically review and estimate pooled sensitivity and specificity of the polymerase chain reaction (PCR) technique compared to recommended reference tests in the diagnosis of suspected syphilis at various stages and in various biological materials.

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