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Nifurtimox-Eflornithine Combination Therapy for Second-Stage Gambiense Human African Trypanosomiasis: Medecins Sans Frontieres Experience in the Democratic Republic of the Congo

Authors
Amici Heradi, J.
de Patoul, C.
Quere, M.
Published in Clinical Infectious Diseases. 2013, vol. 56, no. 2, p. 195-203
Abstract Existing diagnostic and treatment tools for human African trypanosomiasis (HAT) are limited. The recent development of nifurtimox-eflornithine combination therapy (NECT) has brought new hopes for patients in the second stage. While NECT has been rolled out in most endemic countries, safety data are scarce and derive only from clinical trials. The World Health Organization (WHO) coordinates a pharmacovigilance program to collect additional data on NECT safety and efficacy. We report here the results of 18 months of experience of NECT use in treatment centers run by Médecins Sans Frontières in the Democratic Republic of the Congo (DRC).
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PMID: 23074318
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ALIROL, Emilie et al. Nifurtimox-Eflornithine Combination Therapy for Second-Stage Gambiense Human African Trypanosomiasis: Medecins Sans Frontieres Experience in the Democratic Republic of the Congo. In: Clinical Infectious Diseases, 2013, vol. 56, n° 2, p. 195-203. https://archive-ouverte.unige.ch/unige:33849

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Deposited on : 2014-01-29

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