Scientific article

Unconsciousness and sedation as precipitating factors of diabetic ketoacidosis

Published inJournal of forensic and legal medicine, vol. 20, no. 7, p. 830-835
Publication date2013

The aim of this study was to identify medico-legal situations characterized by increased vitreous glucose concentrations, potentially lethal blood 3-hydroxybutyrate levels and conditions that could either incapacitate or lead to death on their own. The above was investigated in order to verify whether prolonged states of unconsciousness may play a role in precipitating diabetic ketoacidosis. Six groups of medico-legal situations (corresponding to 206 autopsy cases) were identified. Among these, three cases were characterized by pathologically increased vitreous glucose and blood 3-hydroxybutyrate levels. In one case diabetic ketoacidosis coexisted with underlying features that might have potentially incapacitated or lead to death on their own, whereas in two cases it corresponded with potentially lethal or lethal drug concentrations. The results of this study highlight the usefulness of systematically performing biochemistry in order to identify diabetic ketoacidosis-related deaths, even when autopsy and toxicology results provide apparently conclusive findings.

Citation (ISO format)
PALMIERE, Cristian et al. Unconsciousness and sedation as precipitating factors of diabetic ketoacidosis. In: Journal of forensic and legal medicine, 2013, vol. 20, n° 7, p. 830–835. doi: 10.1016/j.jflm.2013.06.030
Main files (1)
Article (Accepted version)
ISSN of the journal1752-928X

Technical informations

Creation11/12/2013 9:45:00 AM
First validation11/12/2013 9:45:00 AM
Update time03/14/2023 8:55:18 PM
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