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Scientific article
French

Diabète et ostéoporose

Contributors

Ferrari, Serge Livio

Published in

Revue médicale suisse, vol. 9, no. 390, p. 1256-1259

Publication date

2013

Abstract

Diabetes alters bone mass and/or quality and increases fracture risk. However, in type 2 diabetes, bone mineral density (BMD) is usually not diminished, pertaining to increased weight and fat mass, which complicates the diagnosis of osteoporosis by DXA (T-score <-2.5). Similarly, estimates of fracture probability by FRAX may underestimate fracture risk in type 2 diabetes. Adequate glycemic control with insulin and/or oral antidiabetics decreases fracture risk, whereas thiazolidinediones increase it. Eventually, osteoporosis drugs such as bisphosphonates and SERMs seem to have similar efficacy in diabetic and non-diabetic patients.

Keywords

  • Absorptiometry, Photon
  • Bone Density
  • Bone Density Conservation Agents/therapeutic use
  • Diabetes Mellitus, Type 2/complications/drug therapy
  • Humans
  • Hypoglycemic Agents/adverse effects/therapeutic use
  • Osteoporosis/diagnosis/drug therapy/etiology
  • Osteoporotic Fractures/etiology/prevention & control
  • Selective Estrogen Receptor Modulators/therapeutic use

UNIGE affiliation entities

UNIGE research groups

Citation (ISO format)

FERRARI, Serge Livio. Diabète et ostéoporose. In: Revue médicale suisse, 2013, vol. 9, n° 390, p. 1256–1259.

Main files (1)

Article (Published version)

Identifiers

Additional URL for this publication

http://rms.medhyg.ch/numero-390-page-1256.htm

Journal ISSN

1660-9379
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Technical informations

Creation

20/12/2013 15:12:00

First validation

20/12/2013 15:12:00

Update

14/03/2023 20:53:39

Status update

14/03/2023 20:53:39

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