Regions of interest-based discriminant analysis of DaTSCAN SPECT and FDG-PET for the classification of dementia

Garibotto, Valentina; Montandon, Marie Louise; Viaud, Claire Tabouret; Allaoua, Mohamed; Assal, Frédéric; Burkhard, Pierre; Ratib, Osman; Zaidi, Habib

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Title		Regions of interest-based discriminant analysis of DaTSCAN SPECT and FDG-PET for the classification of dementia
Authors		Garibotto, Valentina Montandon, Marie Louise Viaud, Claire Tabouret Allaoua, Mohamed Assal, Frédéric Burkhard, Pierre Ratib, Osman Zaidi, Habib
Published in		Clinical Nuclear Medicine. 2013, vol. 38, no. 3, p. e112-7
Abstract		Neuroimaging is increasingly used to support the clinical diagnosis of patients with cognitive impairment. Dopamine transporter (DAT) imaging, such as DaTSCAN SPECT, tests the integrity of the nigrostriatal pathway, whereas FDG-PET identifies typical patterns of cortical and subcortical hypometabolism. The aim of this study was to assess the relative contribution of DAT and regional glucose metabolism imaging to the differential diagnosis.
Keywords		Aged — Aged, 80 and over — Biological Transport — Dementia/metabolism/radionuclide imaging — Discriminant Analysis — Dopamine Plasma Membrane Transport Proteins/metabolism — Female — Fluorodeoxyglucose F18/diagnostic use/metabolism — Follow-Up Studies — Humans — Image Processing, Computer-Assisted/methods — Male — Middle Aged — Positron-Emission Tomography/methods — Retrospective Studies — Tomography, Emission-Computed, Single-Photon/methods
Identifiers		DOI: 10.1097/RLU.0b013e318279b991 PMID: 23357822
Full text		Article (Published version) (961 Kb) - Limited access to UNIGE
Structures		Faculté de médecine / Section de médecine clinique / Département des neurosciences cliniques Faculté de médecine / Section de médecine clinique / Département de radiologie et informatique médicale
Research groups		Groupe Pierre Burkhard (neurologie) (154) Groupe Ratib Osman (nouvelles techniques d'imagerie moléculaire) (819) Neuropsychologie et neurologie comportementale (951) Laboratoire de neuroimagerie et de traceurs moléculaires innovants (984)
Citation (ISO format)		GARIBOTTO, Valentina et al. Regions of interest-based discriminant analysis of DaTSCAN SPECT and FDG-PET for the classification of dementia. In: Clinical Nuclear Medicine, 2013, vol. 38, n° 3, p. e112-7. https://archive-ouverte.unige.ch/unige:33610