Scientific article
English

Role of endogenous Fas (CD95/Apo-1) ligand in balloon-induced apoptosis, inflammation, and neointima formation

Published inCirculation, vol. 113, no. 15, p. 1879-1887
Publication date2006
Abstract

Fas (CD95/Apo-1) ligand (FasL)-induced apoptosis in Fas-bearing cells is critically involved in modulating immune reactions and tissue repair. Apoptosis has also been described after mechanical vascular injury such as percutaneous coronary intervention. However, the relevance of cell death in this context of vascular repair remains unknown.

Keywords
  • Animals
  • Anti-Inflammatory Agents/metabolism
  • Apoptosis
  • Carotid Artery Injuries/etiology/pathology
  • Catheterization/adverse effects
  • Cell Movement
  • Cell Proliferation
  • Fas Ligand Protein
  • Lymphoproliferative Disorders/pathology/physiopathology
  • Macrophages/pathology
  • Macrophages, Peritoneal/metabolism
  • Male
  • Membrane Glycoproteins/deficiency/metabolism
  • Mice
  • Mice, Inbred C57BL
  • Mice, Knockout
  • Muscle, Smooth, Vascular/pathology
  • Myocytes, Smooth Muscle/pathology
  • Tumor Necrosis Factors/deficiency/metabolism
  • Tunica Intima/pathology
  • Tunica Media/pathology
Citation (ISO format)
MATTER, Christian M et al. Role of endogenous Fas (CD95/Apo-1) ligand in balloon-induced apoptosis, inflammation, and neointima formation. In: Circulation, 2006, vol. 113, n° 15, p. 1879–1887. doi: 10.1161/CIRCULATIONAHA.106.611731
Main files (1)
Article (Published version)
accessLevelRestricted
Identifiers
Journal ISSN0009-7322
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