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Role of endogenous Fas (CD95/Apo-1) ligand in balloon-induced apoptosis, inflammation, and neointima formation

Publié dansCirculation, vol. 113, no. 15, p. 1879-1887
Date de publication2006
Résumé

Fas (CD95/Apo-1) ligand (FasL)-induced apoptosis in Fas-bearing cells is critically involved in modulating immune reactions and tissue repair. Apoptosis has also been described after mechanical vascular injury such as percutaneous coronary intervention. However, the relevance of cell death in this context of vascular repair remains unknown.

Mots-clés
  • Animals
  • Anti-Inflammatory Agents/metabolism
  • Apoptosis
  • Carotid Artery Injuries/etiology/pathology
  • Catheterization/adverse effects
  • Cell Movement
  • Cell Proliferation
  • Fas Ligand Protein
  • Lymphoproliferative Disorders/pathology/physiopathology
  • Macrophages/pathology
  • Macrophages, Peritoneal/metabolism
  • Male
  • Membrane Glycoproteins/deficiency/metabolism
  • Mice
  • Mice, Inbred C57BL
  • Mice, Knockout
  • Muscle, Smooth, Vascular/pathology
  • Myocytes, Smooth Muscle/pathology
  • Tumor Necrosis Factors/deficiency/metabolism
  • Tunica Intima/pathology
  • Tunica Media/pathology
Groupe de recherche
Citation (format ISO)
MATTER, Christian M et al. Role of endogenous Fas (CD95/Apo-1) ligand in balloon-induced apoptosis, inflammation, and neointima formation. In: Circulation, 2006, vol. 113, n° 15, p. 1879–1887. doi: 10.1161/CIRCULATIONAHA.106.611731
Fichiers principaux (1)
Article (Published version)
accessLevelRestricted
Identifiants
ISSN du journal0009-7322
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Création31/10/2013 15:56:00
Première validation31/10/2013 15:56:00
Heure de mise à jour14/03/2023 20:51:18
Changement de statut14/03/2023 20:51:17
Dernière indexation16/01/2024 08:54:11
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