Can concomitant-boost accelerated radiotherapy be adopted as routine treatment for head-and-neck cancers? A 10-year single-institution experience

Allal, Abdelkarim Said; Taussky, Daniel; Mach, Nicolas; Becker, Minerva; Bieri, Sabine; Dulguerov, Pavel

doi:10.1016/j.ijrobp.2003.09.017

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Title		Can concomitant-boost accelerated radiotherapy be adopted as routine treatment for head-and-neck cancers? A 10-year single-institution experience
Authors		Allal, Abdelkarim Said Taussky, Daniel Mach, Nicolas Becker, Minerva Bieri, Sabine Dulguerov, Pavel
Published in		International Journal of Radiation Oncology, Biology, Physics. 2004, vol. 58, no. 5, p. 1431-6
Abstract		Accelerated schedules are effective in overcoming repopulation during radiotherapy (RT) for head-and-neck cancers, but their feasibility is compromised by increased toxicity. The therapeutic ratio may be particularly favorable for 5-week regimens. This study reports the 10-year experience of a single institution in the routine use of concomitant boost RT as standard radical treatment in all but the most favorable stage patients.
Keywords		Adolescent — Adult — Aged — Aged, 80 and over — Antineoplastic Combined Chemotherapy Protocols/therapeutic use — Carcinoma, Squamous Cell/drug therapy/radiotherapy/surgery — Cause of Death — Cisplatin/administration & dosage — Combined Modality Therapy — Dose Fractionation — Feasibility Studies — Female — Fluorouracil/administration & dosage — Head and Neck Neoplasms/drug therapy/radiotherapy/surgery — Humans — Male — Middle Aged — Statistics as Topic
Identifiers		DOI: 10.1016/j.ijrobp.2003.09.017 PMID: 15050320
Full text		Article (Published version) (71 Kb) - Free access
Structures		Faculté de médecine / Section de médecine clinique / Département de médecine Faculté de médecine / Section de médecine clinique / Département des neurosciences cliniques Faculté de médecine / Section de médecine clinique / Département de radiologie et informatique médicale
Research group		Groupe Dulguerov Pavel (ORL et chirurgie cervico-faciale) (145)
Citation (ISO format)		ALLAL, Abdelkarim Said et al. Can concomitant-boost accelerated radiotherapy be adopted as routine treatment for head-and-neck cancers? A 10-year single-institution experience. In: International Journal of Radiation Oncology, Biology, Physics, 2004, vol. 58, n° 5, p. 1431-6. doi: 10.1016/j.ijrobp.2003.09.017 https://archive-ouverte.unige.ch/unige:33112

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Can concomitant-boost accelerated radiotherapy be adopted as routine treatment for head-and-neck cancers? A 10-year single-institution experience