Phase I trial of concomitant hyperfractionated radiotherapy with docetaxel and cisplatin for locally advanced head and neck cancer

Allal, Abdelkarim Said; Zwahlen, Daniel; Becker, Minerva; Dulguerov, Pavel; Mach, Nicolas

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Title		Phase I trial of concomitant hyperfractionated radiotherapy with docetaxel and cisplatin for locally advanced head and neck cancer
Authors		Allal, Abdelkarim Said Zwahlen, Daniel Becker, Minerva Dulguerov, Pavel Mach, Nicolas
Published in		The cancer journal. 2006, vol. 12, no. 1, p. 63-8
Abstract		This study was conducted to determine the maximum tolerated dose of docetaxel when administered concomitantly with radical hyperfractionated radiotherapy and cisplatin in patients with locally advanced head and neck cancer.
Keywords		Aged — Antineoplastic Combined Chemotherapy Protocols/administration & dosage/adverse effects — Carcinoma, Squamous Cell/pathology/therapy — Cisplatin/administration & dosage/adverse effects — Combined Modality Therapy — Deglutition Disorders/etiology — Dose Fractionation — Dose-Response Relationship, Drug — Female — Head and Neck Neoplasms/pathology/therapy — Humans — Male — Maximum Tolerated Dose — Middle Aged — Mucositis/etiology — Neck Dissection — Neoplasm Staging — Taxoids/administration & dosage/adverse effects — Treatment Outcome
Identifiers		PMID: 16613664
Full text		Article (Published version) (77 Kb) - Free access
Structures		Faculté de médecine / Section de médecine clinique / Département de médecine Faculté de médecine / Section de médecine clinique / Département de radiologie et informatique médicale
Research groups		Groupe Becker Minerva (imagerie ORL) (683) Groupe Dulguerov Pavel (ORL et chirurgie cervico-faciale) (145) La recherche translationnelle en oncologie (654)
Citation (ISO format)		ALLAL, Abdelkarim Said et al. Phase I trial of concomitant hyperfractionated radiotherapy with docetaxel and cisplatin for locally advanced head and neck cancer. In: The cancer journal, 2006, vol. 12, n° 1, p. 63-8. https://archive-ouverte.unige.ch/unige:33098