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Title

In vivo 13C NMR spectroscopy and metabolic modeling in the brain: a practical perspective

Authors
Henry, Pierre-Gilles
Adriany, Gregor
Deelchand, Dinesh
Marjanska, Malgorzata
Oz, Gülin
Seaquist, Elizabeth R
Shestov, Alexander
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Published in Magnetic Resonance Imaging. 2006, vol. 24, no. 4, p. 527-39
Abstract In vivo 13C NMR spectroscopy has the unique capability to measure metabolic fluxes noninvasively in the brain. Quantitative measurements of metabolic fluxes require analysis of the 13C labeling time courses obtained experimentally with a metabolic model. The present work reviews the ingredients necessary for a dynamic metabolic modeling study, with particular emphasis on practical issues.
Keywords AnimalsBrain/metabolismCarbon RadioisotopesMagnetic Resonance SpectroscopyModels, BiologicalRats
Identifiers
PMID: 16677959
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Research group CIBM (863)
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HENRY, Pierre-Gilles et al. In vivo 13C NMR spectroscopy and metabolic modeling in the brain: a practical perspective. In: Magnetic Resonance Imaging, 2006, vol. 24, n° 4, p. 527-39. https://archive-ouverte.unige.ch/unige:32916

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Deposited on : 2014-01-08

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