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Chiari I malformation associated with premature unilateral closure of the posterior intraoccipital synchondrosis in a preterm infant

Kanavaki, Aikaterini
Published in Journal of neurosurgery. Pediatrics. 2013, vol. 11, no. 6, p. 658-60
Abstract The authors report a case of a preterm infant at 29 weeks of gestation who gradually developed a Chiari malformation Type I (CM-I) with hydrocephalus due to a premature unilateral fusion of the posterior intraoccipital synchondrosis. Brain ultrasonography results in the 1st week of life were normal. Follow-up ultrasonography showed progressive development of triventricular hydrocephalus. Brain MRI demonstrated the presence of a CM-I and a deformation of the occipital bone. A complementary CT scan was obtained, showing a closure of the right posterior intraoccipital synchondrosis, resulting in a deformation of the posterior cranial fossa. This case shows the close relationship between a malformation of the skull base and the secondary development of a brain malformation. The authors discuss the anatomy of the occipital bone and suggest a probable theory for the premature closure of this synchondrosis and the consequent development of a CM-I. The originality of this case lies in the observation of the natural history of a brain malformation in a preterm infant.
Keywords Arnold-Chiari Malformation/etiology/radiographyCranial Fossa, Posterior/abnormalitiesCraniosynostoses/complicationsHumansHydrocephalus/etiologyInfantInfant, NewbornInfant, PrematureInfant, Premature, Diseases/diagnosis/pathology/radiographyMagnetic Resonance ImagingMaleOccipital Bone/abnormalities/growth & development/radiographyOsteochondrosis/complicationsSkull Base/abnormalities/radiographyTomography, X-Ray Computed
PMID: 23581638
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Research group Groupe Hanquinet Sylviane (radiologie neuro-diagnostique et neuro-interventionnelle en pédiatrie) (842)
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KANAVAKI, Aikaterini, JENNY, Benoît John, HANQUINET, Sylviane. Chiari I malformation associated with premature unilateral closure of the posterior intraoccipital synchondrosis in a preterm infant. In: Journal of neurosurgery. Pediatrics, 2013, vol. 11, n° 6, p. 658-60. doi: 10.3171/2013.3.PEDS12549 https://archive-ouverte.unige.ch/unige:32606

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Deposited on : 2013-12-20

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