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Scientific article
English

Articular inflammation is controlled by myeloid cell-derived interleukin 1 receptor antagonist during the acute phase of arthritis in mice

Published inAnnals of the rheumatic diseases, vol. 71, no. 2, p. 281-287
Publication date2012
Abstract

To define the cell type (myeloid vs other cells) specific effect of interleukin 1 (IL-1) receptor antagonist (IL-1Ra) deficiency on the acute inflammatory phase of arthritis.

Keywords
  • Acute Disease
  • Animals
  • Arthritis, Experimental/etiology/metabolism/pathology
  • Cartilage, Articular/pathology
  • Disease Progression
  • Female
  • Interleukin 1 Receptor Antagonist Protein/deficiency/physiology
  • Mice
  • Mice, Inbred C57BL
  • Mice, Knockout
  • Myeloid Cells/metabolism
  • Protein Isoforms/deficiency/physiology
  • Serum
  • Severity of Illness Index
  • Synovitis/metabolism/pathology
Citation (ISO format)
LAMACCHIA, Céline et al. Articular inflammation is controlled by myeloid cell-derived interleukin 1 receptor antagonist during the acute phase of arthritis in mice. In: Annals of the rheumatic diseases, 2012, vol. 71, n° 2, p. 281–287. doi: 10.1136/annrheumdis-2011-200429
Main files (1)
Article (Published version)
accessLevelRestricted
Identifiers
ISSN of the journal0003-4967
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