Cell-free screening for NOX inhibitors

Bedard, Karen; Jaquet, Vincent

doi:10.1016/j.chembiol.2012.06.002

Scientific article

English

Cell-free screening for NOX inhibitors

ContributorsBedard, Karen; Jaquet, Vincent

Published inChemistry & biology, vol. 19, no. 6, p. 664-665

Publication date2012

Abstract

NOX enzymes are major ROS generators in pathological states and represent a promising pharmacological target. In this issue of Chemistry & Biology, Smith and colleagues developed an original and elegant cell-free assay to identify specific Nox2 inhibitors in a high throughput manner.

Affiliation

Faculté de médecine / Section de médecine fondamentale / Département de pathologie et immunologie

Research group

Radicaux libres et cellules souches embryonnaires (60)

Citation (ISO format)

BEDARD, Karen, JAQUET, Vincent. Cell-free screening for NOX inhibitors. In: Chemistry & biology, 2012, vol. 19, n° 6, p. 664–665. doi: 10.1016/j.chembiol.2012.06.002

Article (Published version)

Identifiers

PID : unige:32454
DOI : 10.1016/j.chembiol.2012.06.002
PMID : 22726678

ISSN of the journal1074-5521

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Cell-free screening for NOX inhibitors

NOX enzymes are major ROS generators in pathological states and represent a promising pharmacological target. In this issue of Chemistry & Biology, Smith and colleagues developed an original and elegant cell-free assay to identify specific Nox2 inhibitors in a high throughput manner.

Technical informations