The impact of antibiotic use on the incidence and resistance pattern of extended-spectrum beta-lactamase-producing bacteria in primary and secondary healthcare settings

Aldeyab, Mamoon A; Harbarth, Stéphan Juergen; Vernaz, Nathalie; Kearney, Mary P; Scott, Michael G; Darwish Elhajji, Feras W; Aldiab, Motasem A; McElnay, James C

doi:10.1111/j.1365-2125.2011.04161.x

Scientific article

English

The impact of antibiotic use on the incidence and resistance pattern of extended-spectrum beta-lactamase-producing bacteria in primary and secondary healthcare settings

ContributorsAldeyab, Mamoon A; Harbarth, Stéphan Juergen

; Vernaz, Nathalie; Kearney, Mary P; Scott, Michael G; Darwish Elhajji, Feras W; Aldiab, Motasem A; McElnay, James C

Published inBritish journal of clinical pharmacology, vol. 74, no. 1, p. 171-179

Publication date2012

Abstract

• The emergence and spread of bacteria producing extended-spectrum beta-lactamases (ESBLs) has important therapeutic and epidemiologic implications. • A key target for the establishment of hospital antibiotic stewardship is reducing the occurrence of additional antibiotic resistance. • Further research is needed to accumulate supporting evidence that reducing antibiotic use will result in a parallel reduction in antibiotic resistance.

Keywords

Amoxicillin-Potassium Clavulanate Combination/therapeutic use
Anti-Bacterial Agents/therapeutic use
Bacteria/drug effects
Cross Infection/microbiology/prevention & control
Disinfectants/therapeutic use
Fluoroquinolones/therapeutic use
Hospitals
Humans
Incidence
Multivariate Analysis
Primary Health Care
Regression Analysis
Retrospective Studies
Risk Factors
Beta-Lactam Resistance/drug effects
Beta-Lactamases/antagonists & inhibitors/metabolism

Affiliation entities

Faculté de médecine / Section de médecine clinique / Département de médecine

Research groups

Résistance aux antibiotiques (866)

Citation (ISO format)

ALDEYAB, Mamoon A et al. The impact of antibiotic use on the incidence and resistance pattern of extended-spectrum beta-lactamase-producing bacteria in primary and secondary healthcare settings. In: British journal of clinical pharmacology, 2012, vol. 74, n° 1, p. 171–179. doi: 10.1111/j.1365-2125.2011.04161.x

Article (Published version)

Identifiers

PID : unige:32400
DOI : 10.1111/j.1365-2125.2011.04161.x
PMID : 22150975

Journal ISSN0306-5251

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The impact of antibiotic use on the incidence and resistance pattern of extended-spectrum beta-lactamase-producing bacteria in primary and secondary healthcare settings

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