Adipocyte dysfunction in a mouse model of polycystic ovary syndrome (PCOS): evidence of adipocyte hypertrophy and tissue-specific inflammation
Published inPloS one, vol. 7, no. 10, e48643
Publication date2012
Abstract
Keywords
- Adipocytes/metabolism/pathology
- Adipose Tissue/metabolism/pathology
- Animals
- Blood Glucose/metabolism
- Disease Models, Animal
- Female
- Gene Expression
- Humans
- Hypertrophy
- Inflammation/genetics/metabolism
- Interleukin-1beta/blood/genetics/metabolism
- Interleukin-6/blood/genetics/metabolism
- Liver/metabolism/pathology
- Magnetic Resonance Imaging
- Male
- Mice
- Mice, Knockout
- Ovary/metabolism/pathology
- Ovulation/genetics
- Polycystic Ovary Syndrome/blood/genetics/metabolism
- Pregnancy
- Receptor, Insulin/genetics/metabolism
- Receptors, Leptin/genetics/metabolism
- Reverse Transcriptase Polymerase Chain Reaction
- Tomography, X-Ray Computed
Research group
Citation (ISO format)
MARINO, Joseph S et al. Adipocyte dysfunction in a mouse model of polycystic ovary syndrome (PCOS): evidence of adipocyte hypertrophy and tissue-specific inflammation. In: PloS one, 2012, vol. 7, n° 10, p. e48643. doi: 10.1371/journal.pone.0048643
Main files (1)
Article (Published version)
Identifiers
- PID : unige:32259
- DOI : 10.1371/journal.pone.0048643
- PMID : 23119079
ISSN of the journal1932-6203