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Title

Intensity modulated proton and photon therapy for early prostate cancer with or without transperineal injection of a polyethylen glycol spacer: a treatment planning comparison study
Authors
Weber, Damien
Zilli, Thomas
Vallée, Jean-Paul
Rouzaud, Michel
Miralbell, Raymond
Cozzi, Luca
Published in International Journal of Radiation Oncology, Biology, Physics. 2012, vol. 84, no. 3, p. e311-8
Abstract Rectal toxicity is a serious adverse effect in early-stage prostate cancer patients treated with curative radiation therapy (RT). Injecting a spacer between Denonvilliers' fascia increases the distance between the prostate and the anterior rectal wall and may thus decrease the rectal radiation-induced toxicity. We assessed the dosimetric impact of this spacer with advanced delivery RT techniques, including intensity modulated RT (IMRT), volumetric modulated arc therapy (VMAT), and intensity modulated proton beam RT (IMPT).
Keywords Absorbable Implants — Aged — Humans — Male — Middle Aged — Photons/therapeutic use — Polyethylene Glycols/administration & dosage — Prostate/radiography — Prostatic Neoplasms/pathology/radiography/radiotherapy — Protons/therapeutic use — Radiation Injuries/prevention & control — Radiotherapy Dosage — Radiotherapy Planning, Computer-Assisted/methods — Radiotherapy, Intensity-Modulated/methods — Rectum/radiation effects/radiography — Urinary Bladder/radiation effects/radiography
Identifiers
PMID: 22999271
Full text
Article (Published version) (715 Kb) - document accessible for UNIGE members only Limited access to UNIGE
Structures
Faculté de médecine / Section de médecine clinique / Département de radiologie et informatique médicale
Research groups Imagerie cardiaque fonctionnelle (541)
Groupe Mirabell Raymond (radio-oncologie) (685)
Citation
(ISO format) 		WEBER, Damien et al. Intensity modulated proton and photon therapy for early prostate cancer with or without transperineal injection of a polyethylen glycol spacer: a treatment planning comparison study. In: International Journal of Radiation Oncology, Biology, Physics, 2012, vol. 84, n° 3, p. e311-8. https://archive-ouverte.unige.ch/unige:32078

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Deposited on : 2013-12-13

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