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Title

Intensity modulated proton and photon therapy for early prostate cancer with or without transperineal injection of a polyethylen glycol spacer: a treatment planning comparison study

Authors
Rouzaud, Michel
Cozzi, Luca
Published in International Journal of Radiation Oncology, Biology, Physics. 2012, vol. 84, no. 3, p. e311-8
Abstract Rectal toxicity is a serious adverse effect in early-stage prostate cancer patients treated with curative radiation therapy (RT). Injecting a spacer between Denonvilliers' fascia increases the distance between the prostate and the anterior rectal wall and may thus decrease the rectal radiation-induced toxicity. We assessed the dosimetric impact of this spacer with advanced delivery RT techniques, including intensity modulated RT (IMRT), volumetric modulated arc therapy (VMAT), and intensity modulated proton beam RT (IMPT).
Keywords Absorbable ImplantsAgedHumansMaleMiddle AgedPhotons/therapeutic usePolyethylene Glycols/administration & dosageProstate/radiographyProstatic Neoplasms/pathology/radiography/radiotherapyProtons/therapeutic useRadiation Injuries/prevention & controlRadiotherapy DosageRadiotherapy Planning, Computer-Assisted/methodsRadiotherapy, Intensity-Modulated/methodsRectum/radiation effects/radiographyUrinary Bladder/radiation effects/radiography
Identifiers
PMID: 22999271
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Structures
Research groups Imagerie cardiaque fonctionnelle (541)
Groupe Mirabell Raymond (radio-oncologie) (685)
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(ISO format)
WEBER, Damien et al. Intensity modulated proton and photon therapy for early prostate cancer with or without transperineal injection of a polyethylen glycol spacer: a treatment planning comparison study. In: International Journal of Radiation Oncology, Biology, Physics, 2012, vol. 84, n° 3, p. e311-8. https://archive-ouverte.unige.ch/unige:32078

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Deposited on : 2013-12-13

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