Scientific article
Azithromycin to prevent Pseudomonas aeruginosa ventilator-associated pneumonia by inhibition of quorum sensing: a randomized controlled trial
Published inIntensive care medicine, vol. 38, no. 7, p. 1118-1125
Publication date2012
Abstract
Keywords
- Anti-Bacterial Agents/therapeutic use
- Antibiotic Prophylaxis
- Azithromycin/pharmacology/therapeutic use
- Double-Blind Method
- Female
- Glycolipids/pharmacology/therapeutic use
- Humans
- Male
- Middle Aged
- Pilot Projects
- Pneumonia, Ventilator-Associated/drug therapy/microbiology/prevention & control
- Pseudomonas Infections/drug therapy/microbiology/prevention & control
- Pseudomonas aeruginosa/drug effects/pathogenicity
- Quorum Sensing/drug effects
- Virulence/drug effects
Affiliation entities
Research groups
Funding
- Swiss National Science Foundation - Novel appproaches to detect and circumvent antibiotic resistance in Pseudomonas aeruginosa [63239]
- Swiss National Science Foundation - Adaptation of Pseudomonas aeruginosa during respiratory tract colonization and infection in mechanically ventilated patients: in vitro and in situ studies [108106]
Citation (ISO format)
VAN DELDEN, Christian et al. Azithromycin to prevent Pseudomonas aeruginosa ventilator-associated pneumonia by inhibition of quorum sensing: a randomized controlled trial. In: Intensive care medicine, 2012, vol. 38, n° 7, p. 1118–1125. doi: 10.1007/s00134-012-2559-3
Main files (1)
Article (Published version)
Identifiers
- PID : unige:32040
- DOI : 10.1007/s00134-012-2559-3
- PMID : 22527075
Journal ISSN0342-4642
