UNIGE document Scientific Article - Review
previous document  unige:31891  next document
add to browser collection
Title

Latest Developments in Assessing Antifungal Activity Using TLC-Bioautography: A Review

Authors
Published in Journal of AOAC International. 2013, vol. 96, no. 6, p. 1175-1188
Abstract This paper reviews the use of TLC-bioautography in the search for antifungal compounds from natural sources. The main methods used for antifungal screening are presented, with special emphasis on bioautography. Different aspects of the technique, including the latest chromatographic developments such as HPTLC and HPLC microfractionation are presented. The present status and recent advances made in antifungal bioautography are discussed, and a comprehensive review of the applications over the last 6 years is presented. Various strategies applied in the search for antifungal compounds from natural sources are discussed, with a highlight on the challenges faced when screening complex crude mixtures. The activities of approximately 100 antifungal compounds of natural origin are presented with their minimum inhibitory quantity. The most active natural source compounds against Candida, Cladosporium, Colletotrichum, and Fusarium species are highlighted, and the compound activities discussed. In addition, perspectives concerning future improvements in bioautography sensitivity and reproducibility are noted.
Keywords AntifungalTLC-bioautographyNatural sources
Identifiers
Full text
Article (Published version) (997 Kb) - document accessible for UNIGE members only Limited access to UNIGE
Other version: http://dx.doi.org/10.5740/jaoacint.SGEFavre-Godal
Structures
Research group Phytochimie et produits naturels bioactifs
Citation
(ISO format)
FAVRE-GODAL, Quentin, FERREIRA QUEIROZ, Emerson, WOLFENDER, Jean-Luc. Latest Developments in Assessing Antifungal Activity Using TLC-Bioautography: A Review. In: Journal of AOAC International, 2013, vol. 96, n° 6, p. 1175-1188. https://archive-ouverte.unige.ch/unige:31891

248 hits

8 downloads

Update

Deposited on : 2013-12-09

Export document
Format :
Citation style :