Scientific article

Prévention de l'hyperalgésie en postopératoire

ContributorsMamie, Chantal
Published inAnnales françaises d'anesthésie et de réanimation, vol. 31, no. 1, p. e39-42
Publication date2012

Three types of hyperalgesia can occur during the postoperative period: primary hyperalgesia, which disappears with wound healing, secondary or central hyperalgesia, which can lead to chronic pain, and opiate-induced hyperalgesia. Different drugs, most of which are NMDA receptors antagonists, are used to decrease or prevent the risk of central or opiate-induced hyperalgesia. However, it is difficult to determine whether they are really effective and at which dosage: the results of most published studies are difficult to interpret because of methodological problems. The two most frequent of those are: absence of objective measurement of secondary hyperalgesia and difficulties targeting an at risk population.

  • Amantadine/therapeutic use
  • Amines/therapeutic use
  • Analgesics, Non-Narcotic/therapeutic use
  • Analgesics, Opioid/adverse effects/therapeutic use
  • Cyclohexanecarboxylic Acids/therapeutic use
  • Excitatory Amino Acid Antagonists/therapeutic use
  • Humans
  • Hyperalgesia/chemically induced/etiology/prevention & control
  • Ketamine/therapeutic use
  • Magnesium Compounds/therapeutic use
  • Pain Management/methods
  • Pain, Postoperative/chemically induced/prevention & control
  • Receptors, N-Methyl-D-Aspartate/antagonists & inhibitors
  • Risk Assessment
  • Gamma-Aminobutyric Acid/therapeutic use
NoteCongrès de l'Adarpef - Texte présenté au 31e Congrès national de l'association des anesthésistes réanimateurs pédiatriques d'expression française, 1er – 2 avril 2011 à Reims.
Citation (ISO format)
MAMIE, Chantal. Prévention de l’hyperalgésie en postopératoire. In: Annales françaises d’anesthésie et de réanimation, 2012, vol. 31, n° 1, p. e39–42. doi: 10.1016/j.annfar.2011.11.002
Main files (1)
Article (Published version)
ISSN of the journal0750-7658

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