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Title

Minor protease inhibitor mutations at baseline do not increase the risk for a virological failure in HIV-1 subtype B infected patients

Authors
Scherrer, Alexandra U
Ledergerber, Bruno
von Wyl, Viktor
Böni, Jürg
Klimkait, Thomas
Cellerai, Cristina
Furrer, Hansjakob
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Published in PLOS ONE. 2012, vol. 7, no. 6, p. e37983
Abstract Minor protease inhibitor (PI) mutations often exist as polymorphisms in HIV-1 sequences from treatment-naïve patients. Previous studies showed that their presence impairs the antiretroviral treatment (ART) response. Evaluating these findings in a larger cohort is essential.
Keywords CD4 Lymphocyte CountDrug Resistance, Viral/geneticsFemaleHIV Infections/drug therapy/virologyHIV Protease/geneticsHIV Protease Inhibitors/pharmacology/therapeutic useHumansMaleMutationRNA, Viral/bloodViral Load
Identifiers
PMID: 22719859
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Research group VIH/SIDA (930)
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SCHERRER, Alexandra U et al. Minor protease inhibitor mutations at baseline do not increase the risk for a virological failure in HIV-1 subtype B infected patients. In: PLOS ONE, 2012, vol. 7, n° 6, p. e37983. https://archive-ouverte.unige.ch/unige:31692

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Deposited on : 2013-12-04

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