en
Scientific article
Open access
English

Minor protease inhibitor mutations at baseline do not increase the risk for a virological failure in HIV-1 subtype B infected patients

Published inPloS one, vol. 7, no. 6, e37983
Publication date2012
Abstract

Minor protease inhibitor (PI) mutations often exist as polymorphisms in HIV-1 sequences from treatment-naïve patients. Previous studies showed that their presence impairs the antiretroviral treatment (ART) response. Evaluating these findings in a larger cohort is essential.

Keywords
  • CD4 Lymphocyte Count
  • Drug Resistance, Viral/genetics
  • Female
  • HIV Infections/drug therapy/virology
  • HIV Protease/genetics
  • HIV Protease Inhibitors/pharmacology/therapeutic use
  • Humans
  • Male
  • Mutation
  • RNA, Viral/blood
  • Viral Load
Research group
Citation (ISO format)
SCHERRER, Alexandra U et al. Minor protease inhibitor mutations at baseline do not increase the risk for a virological failure in HIV-1 subtype B infected patients. In: PloS one, 2012, vol. 7, n° 6, p. e37983. doi: 10.1371/journal.pone.0037983
Main files (1)
Article (Published version)
Identifiers
ISSN of the journal1932-6203
555views
205downloads

Technical informations

Creation12/03/2013 1:53:00 PM
First validation12/03/2013 1:53:00 PM
Update time03/14/2023 8:40:32 PM
Status update03/14/2023 8:40:31 PM
Last indexation02/12/2024 11:18:03 AM
All rights reserved by Archive ouverte UNIGE and the University of GenevaunigeBlack