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Title

Innate immune deficiency of extremely premature neonates can be reversed by interferon-γ
Authors
Tissières, Pierre
Ochoda, Agnieszka
Dunn-Siegrist, Irène
Drifte Roduit, Geneviève Sophie
Morales, Michel Ange
Pfister, Riccardo
Berner, Michel
Pugin, Jérôme
Published in PloS one. 2012, vol. 7, no. 3, e32863
Abstract Bacterial sepsis is a major threat in neonates born prematurely, and is associated with elevated morbidity and mortality. Little is known on the innate immune response to bacteria among extremely premature infants.
Keywords Body Weight — Cell Line — Female — Fetal Blood/cytology/immunology — Flow Cytometry — Gestational Age — Humans — Immunity, Innate/immunology — Infant, Extremely Low Birth Weight/immunology — Infant, Newborn — Infant, Premature/immunology — Interferon-gamma/therapeutic use — Leukocytes/metabolism — Male — Phagocytosis/physiology — Pregnancy — Receptors, Immunologic/metabolism — Sepsis/drug therapy/immunology — Statistics, Nonparametric
Identifiers
PMID: 22427899
Full text
Article (Published version) (838 Kb) - public document Free access
Structures
Faculté de médecine / Section de médecine clinique / Département de pédiatrie, gynécologie et obstétrique
Faculté de médecine / Section de médecine fondamentale / Département de microbiologie et médecine moléculaire
Research groups Groupe Pugin Jérôme (Soins intensifs) (587)
Maladies pulmonaires aigues et pathologies cardiaques congénitales (697)
Réanimation néonatale en salle d'accouchement (696)
Citation
(ISO format) 		TISSIÈRES, Pierre et al. Innate immune deficiency of extremely premature neonates can be reversed by interferon-γ. In: PloS one, 2012, vol. 7, n° 3, p. e32863. doi: 10.1371/journal.pone.0032863 https://archive-ouverte.unige.ch/unige:31686

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Deposited on : 2013-12-04

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