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Innate immune deficiency of extremely premature neonates can be reversed by interferon-γ |
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Authors | ||
Published in | PloS one. 2012, vol. 7, no. 3, e32863 | |
Abstract | Bacterial sepsis is a major threat in neonates born prematurely, and is associated with elevated morbidity and mortality. Little is known on the innate immune response to bacteria among extremely premature infants. | |
Keywords | Body Weight — Cell Line — Female — Fetal Blood/cytology/immunology — Flow Cytometry — Gestational Age — Humans — Immunity, Innate/immunology — Infant, Extremely Low Birth Weight/immunology — Infant, Newborn — Infant, Premature/immunology — Interferon-gamma/therapeutic use — Leukocytes/metabolism — Male — Phagocytosis/physiology — Pregnancy — Receptors, Immunologic/metabolism — Sepsis/drug therapy/immunology — Statistics, Nonparametric | |
Identifiers | PMID: 22427899 | |
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Research groups | Groupe Pugin Jérôme (Soins intensifs) (587) Maladies pulmonaires aigues et pathologies cardiaques congénitales (697) Réanimation néonatale en salle d'accouchement (696) | |
Citation (ISO format) | TISSIÈRES, Pierre et al. Innate immune deficiency of extremely premature neonates can be reversed by interferon-γ. In: PloS one, 2012, vol. 7, n° 3, p. e32863. doi: 10.1371/journal.pone.0032863 https://archive-ouverte.unige.ch/unige:31686 |