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Co-infection tuberculose et VIH: enjeux thérapeutiques

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Published in Revue médicale suisse. 2011, vol. 7, no. 318, p. 2295-6,2298-300
Abstract Tuberculosis (TB) is the most frequent opportunistic infection in patients infected by the Human immunodeficiency virus (HIV). The mortality related to this co-infection can be reduced by the early introduction of an antiretroviral treatment. However, when treating subjects with TB and HIV, interactions between antiretroviral and tuberculostatic treatments can be problematic; also, these patients may develop, under treatment, an immune reconstitution inflammatory syndrome (IRIS). This review aims to summarize the necessary therapeutic adjustments which should be performed when treating patients co-infected with TB and HIV, the most important interactions between HIV and TB treatments, and the medical management of the IRIS.
Keywords AIDS-Related Opportunistic Infections/drug therapyAntiretroviral Therapy, Highly Active/adverse effectsAntitubercular Agents/adverse effects/therapeutic useChoice BehaviorCoinfection/drug therapyHIV Infections/complications/drug therapyHumansImmune Reconstitution Inflammatory Syndrome/chemically inducedModels, BiologicalTuberculosis/complications/drug therapy
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PMID: 22400365
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Other version: http://rms.medhyg.ch/numero-318-page-2295.htm
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Research group VIH/SIDA (930)
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CHARBONNIER, Florian, CALMY, Alexandra, JANSSENS, Jean-Paul. Co-infection tuberculose et VIH: enjeux thérapeutiques. In: Revue médicale suisse, 2011, vol. 7, n° 318, p. 2295-6,2298-300. https://archive-ouverte.unige.ch/unige:31631

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Deposited on : 2013-12-03

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