en
Scientific article
Open access
English

Long-lasting protection of activity of nucleoside reverse transcriptase inhibitors and protease inhibitors (PIs) by boosted PI containing regimens

Published inPloS one, vol. 7, no. 11, e50307
Publication date2012
Abstract

The accumulation of mutations after long-lasting exposure to a failing combination antiretroviral therapy (cART) is problematic and severely reduces the options for further successful treatments.

Keywords
  • Adult
  • Anti-HIV Agents/administration & dosage/therapeutic use
  • Antiretroviral Therapy, Highly Active
  • Cohort Studies
  • Drug Resistance, Viral/genetics
  • Female
  • Genotype
  • HIV Infections/drug therapy/virology
  • HIV-1/drug effects/genetics
  • Humans
  • Male
  • Middle Aged
  • Mutation
  • Protease Inhibitors/administration & dosage/therapeutic use
  • Reverse Transcriptase Inhibitors/administration & dosage/therapeutic use
  • Risk Factors
  • Time Factors
  • Treatment Failure
  • Viral Load
Research group
Citation (ISO format)
SCHERRER, Alexandra U et al. Long-lasting protection of activity of nucleoside reverse transcriptase inhibitors and protease inhibitors (PIs) by boosted PI containing regimens. In: PloS one, 2012, vol. 7, n° 11, p. e50307. doi: 10.1371/journal.pone.0050307
Main files (1)
Article (Published version)
Identifiers
ISSN of the journal1932-6203
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244downloads

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