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Systemic-onset juvenile idiopathic arthritis: the changing life of a rare disease

Cimaz, Rolando
Von Scheven, Annette
Published in Schweizerische medizinische Wochenschrift. 2012, vol. 142, w13582
Abstract Systemic-onset juvenile idiopathic arthritis (SoJIA), sometimes called Still's disease, is a systemic inflammatory disease classified within the spectrum of juvenile idiopathic arthritis (JIA). It is an orphan disease with often a chronic course and a major impact on the affected children and their families. This disorder is unique in terms of clinical manifestations, prognosis and response to conventional immunosuppressants. The objectives of this review are to describe SoJIA and emphasise the recent advances in the pathogenesis and treatment, which have transformed the care and the prognosis of this potentially life-threatening paediatric condition.
Keywords Anti-Inflammatory Agents, Non-Steroidal/therapeutic useAntibodies, Monoclonal, Humanized/therapeutic useAntirheumatic Agents/therapeutic useArthritis, Juvenile Rheumatoid/complications/diagnosis/drug therapyChild, PreschoolExanthema/etiologyFemaleFever/etiologyHumansIndomethacin/therapeutic useMethotrexate/therapeutic useQuality of LifeSteroids/therapeutic use
PMID: 22573189
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Research group Pathogénèse du syndrome néphrotique idiopathique de l'enfant (180)
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CIMAZ, Rolando, VON SCHEVEN, Annette, HOFER, Michael. Systemic-onset juvenile idiopathic arthritis: the changing life of a rare disease. In: Schweizerische medizinische Wochenschrift, 2012, vol. 142, p. w13582. doi: 10.4414/smw.2012.13582 https://archive-ouverte.unige.ch/unige:31425

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Deposited on : 2013-11-27

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