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Inappropriate antidiuretic hormone secretion: long-term successful urea treatment

Chehade, Hassib
Rosato, Luigi
Cachat, Francois
Published in Acta pædiatrica. 2012, vol. 101, no. 1, p. e39-42
Abstract Hyponatremia is the main complication of inappropriate antidiuretic hormone secretion (SIADH), sometimes fatal. Treatment strategy depends on the cause and the severity of the hyponatremia. Recent studies have shown the efficacy of urea in treating acute hyponatremia secondary to SIADH, by inducing an osmotic water drive. We describe an infant with chronic hyponatremia secondary to SIADH in which the long-term oral treatment with urea was successful and well tolerated. The aim of this paper is to highlight the potential benefits of urea treatment in case of chronic hyponatremia secondary to SIADH.
Keywords Child, PreschoolChronic DiseaseDiuretics, Osmotic/therapeutic useFemaleHumansHyponatremia/drug therapy/etiologyInappropriate ADH Syndrome/complicationsInfantInfant, NewbornLong-Term CareTreatment OutcomeUrea/therapeutic use
PMID: 21672011
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Research group Pathogénèse du syndrome néphrotique idiopathique de l'enfant (180)
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CHEHADE, Hassib et al. Inappropriate antidiuretic hormone secretion: long-term successful urea treatment. In: Acta pædiatrica, 2012, vol. 101, n° 1, p. e39-42. doi: 10.1111/j.1651-2227.2011.02382.x https://archive-ouverte.unige.ch/unige:31424

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Deposited on : 2013-11-27

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