Scientific article
Case report

Inappropriate antidiuretic hormone secretion: long-term successful urea treatment

Published inActa pædiatrica, vol. 101, no. 1, p. e39-42
Publication date2012

Hyponatremia is the main complication of inappropriate antidiuretic hormone secretion (SIADH), sometimes fatal. Treatment strategy depends on the cause and the severity of the hyponatremia. Recent studies have shown the efficacy of urea in treating acute hyponatremia secondary to SIADH, by inducing an osmotic water drive. We describe an infant with chronic hyponatremia secondary to SIADH in which the long-term oral treatment with urea was successful and well tolerated. The aim of this paper is to highlight the potential benefits of urea treatment in case of chronic hyponatremia secondary to SIADH.

  • Child, Preschool
  • Chronic Disease
  • Diuretics, Osmotic/therapeutic use
  • Female
  • Humans
  • Hyponatremia/drug therapy/etiology
  • Inappropriate ADH Syndrome/complications
  • Infant
  • Infant, Newborn
  • Long-Term Care
  • Treatment Outcome
  • Urea/therapeutic use
Citation (ISO format)
CHEHADE, Hassib et al. Inappropriate antidiuretic hormone secretion: long-term successful urea treatment. In: Acta pædiatrica, 2012, vol. 101, n° 1, p. e39–42. doi: 10.1111/j.1651-2227.2011.02382.x
Main files (1)
Article (Published version)
ISSN of the journal0803-5253

Technical informations

Creation10/10/2013 2:21:00 PM
First validation10/10/2013 2:21:00 PM
Update time03/14/2023 8:38:42 PM
Status update03/14/2023 8:38:42 PM
Last indexation01/16/2024 8:16:13 AM
All rights reserved by Archive ouverte UNIGE and the University of GenevaunigeBlack