en
Scientific article
Case report
English

Acute norovirus-induced agranulocytosis in a pediatric kidney transplant recipient

Published inTransplant infectious disease, vol. 14, no. 4, p. E27-29
Publication date2012
Abstract

Norovirus (NoV) infection is usually limited to the gastrointestinal (GI) tract. However, in immunocompromised patients, this infection might lead to severe life-threatening complications. We herein describe a pediatric kidney transplant patient who presented with an acute NoV infection complicated by febrile agranulocytosis that resolved with improvement of her GI illness. This unusual presentation has not been described before, to our knowledge. The aim of this article is to highlight the sometimes dramatic clinical presentation of NoV infection in immunosuppressed patients, and the importance of including this infection in the differential diagnosis of neutropenia in that specific population.

Keywords
  • Acute Disease
  • Agranulocytosis/virology
  • Caliciviridae Infections/complications/virology
  • Child
  • Female
  • Humans
  • Immunocompromised Host
  • Kidney Transplantation/adverse effects
  • Norovirus/pathogenicity
Citation (ISO format)
CHEHADE, H et al. Acute norovirus-induced agranulocytosis in a pediatric kidney transplant recipient. In: Transplant infectious disease, 2012, vol. 14, n° 4, p. E27–29. doi: 10.1111/j.1399-3062.2012.00754.x
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Article (Published version)
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Identifiers
ISSN of the journal1398-2273
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