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Nouvelles thérapies en rhumatologie pédiatrique

Enders, Felicitas Bellutti
Von Scheven-Gête, Annette
Fonjallaz, Béatrice
Published in Revue médicale suisse. 2012, vol. 8, no. 329, p. 418-22
Abstract Biotherapies are recent treatments, which target molecules implicated in the pathogenesis of inflammatory diseases. In pediatric rheumatology, we use anti-TNF-alpha and abatacept in JIA patients with polyarticular involvement, whereas anti-IL-6 and anti-IL-1 blockers are efficacious in the systemic form of JIA and other auto-inflammatory conditions. These new treatments have significantly improved the control of articular and systemic inflammation and the prognosis of rheumatic diseases. Their effect and their safety on the long-term need to be assessed on large cohorts of patients. Due to the impact of these chronic illnesses on the young patient and its family, and the required specific knowledge, the care of these children should be provided by a multidisciplinary team linked to a centre of competence.
Keywords Biological Agents/therapeutic useChildHumansRheumatic Diseases/drug therapy
PMID: 22432243
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Other version: http://rms.medhyg.ch/numero-329-page-418.htm
Research group Pathogénèse du syndrome néphrotique idiopathique de l'enfant (180)
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ENDERS, Felicitas Bellutti et al. Nouvelles thérapies en rhumatologie pédiatrique. In: Revue médicale suisse, 2012, vol. 8, n° 329, p. 418-22. https://archive-ouverte.unige.ch/unige:31368

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Deposited on : 2013-11-27

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