Scientific article

Nouvelles thérapies pour les maladies osseuses de l'enfant

Published inRevue médicale suisse, vol. 8, no. 329, p. 398-402
Publication date2012

Considerable progress has been achieved in recent years in treating children affected by bone diseases. Advances in the understanding of the molecular pathophysiology of genetic bone diseases have led to the development of enzyme replacement therapies for various lysosomal storage diseases, following the breakthrough initiated in treating Gaucher disease. Clinical studies are underway with tailored molecules correcting bone fragility and alleviating chronic bone pain and other manifestations of hypophosphatasia, or promoting growth of long bones in achondroplasia patients. We further report our very encouraging experience with intravenous bisphosphonate treatment in children suffering from secondary osteopenia and the high prevalence of calcium and vitamin D deficits in these severely disabled children.

  • Bone Diseases/drug therapy
  • Child
  • Humans
Citation (ISO format)
BALLHAUSEN, Diana et al. Nouvelles thérapies pour les maladies osseuses de l’enfant. In: Revue médicale suisse, 2012, vol. 8, n° 329, p. 398–402.
Main files (1)
Article (Published version)
ISSN of the journal1660-9379

Technical informations

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