UNIGE document Scientific Article - Case report
previous document  unige:30981  next document
add to browser collection

Partial rhombencephalosynapsis and Chiari type II malformation in a child: a true association supported by DTI tractography

Published in Cerebellum. 2012, vol. 11, no. 1, p. 227-32
Collection Open Access - Licence nationale Springer
Abstract Partial rhombencephalosynapsis (PRECS) has been recently reported in association with Chiari II (CII). However, its existence as a true malformation is challenged due to the anatomical changes potentially induced by CII. The aim of this report was to investigate the contribution of midbrain/hindbrain tractography in this setting. A 13-year-old boy with a known CII malformation and operated myelomeningocele was referred for brain imaging after a first complex partial seizure. In addition to the classical features of CII, MRI showed partially fused cerebellar hemispheres and multiple supratentorial abnormalities. Diffusion tensor imaging (DTI) color map and tractography showed absent transverse fibers on the midsection of the cerebellum, scarce fibers of the middle cerebellar peduncle (MCP), absence of the middle pontine crossing tract, and fibers running vertically in the medial part of the cerebellum. Vertical mediocerebellar fibers are a feature of classical RECS and the paucity or absence of MCP fibers is mainly described in CII. In our patient, DTI and FT therefore demonstrated structural characteristics of both RECS and CII confirming their potential coexistence and suggesting possible shared embryological pathway.
Keywords AdolescentArnold-Chiari Malformation/complications/diagnosis/pathologyDiffusion Tensor Imaging/methodsEpilepsy, Complex Partial/diagnosis/etiology/pathologyHumansMaleNervous System Malformations/diagnosis/etiology/pathologyRhombencephalon/abnormalities/pathology
PMID: 21833660
Full text
Article (Published version) (1.1 MB) - public document Free access
Research groups Groupe Hanquinet Sylviane (radiologie neuro-diagnostique et neuro-interventionnelle en pédiatrie (842)
Groupe Menache Starobinski Caroline (881)
(ISO format)
MERLINI, Laura et al. Partial rhombencephalosynapsis and Chiari type II malformation in a child: a true association supported by DTI tractography. In: Cerebellum, 2012, vol. 11, n° 1, p. 227-32. doi: 10.1007/s12311-011-0300-3 https://archive-ouverte.unige.ch/unige:30981

485 hits



Deposited on : 2013-11-07

Export document
Format :
Citation style :