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Title

Is Cystatin C a promising marker of renal function, at birth, in neonates prenatally diagnosed with congenital kidney anomalies?

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Published in Nephrology, dialysis, transplantation. 2012, vol. 27, no. 9, p. 3477-82
Abstract Despite the increased prenatal diagnosis of congenital abnormalities of the kidney and urinary tract (CAKUT), no reliable renal marker for glomerular filtration rate (GFR) has been validated yet in neonates. Cystatin C (CysC) is specific to the neonate and is proposed as a sensitive marker for this population. The aims of the study were first to define a reference interval in our center of CysC at birth in normal term babies and assess CysC as a marker of GFR in a group of term neonates prenatally diagnosed with CAKUT compared to controls.
Keywords Biological Markers/bloodCystatin C/bloodFemaleGlomerular Filtration RateHumansInfant, NewbornKidney Diseases/blood/congenital/diagnosisMalePrognosisROC Curve
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PMID: 22474211
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Article (Published version) (223 Kb) - document accessible for UNIGE members only Limited access to UNIGE
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Research groups Pathogénèse du syndrome néphrotique idiopathique de l'enfant (180)
Epidémiologie clinique (115)
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PARVEX, Paloma Maria et al. Is Cystatin C a promising marker of renal function, at birth, in neonates prenatally diagnosed with congenital kidney anomalies?. In: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2012, vol. 27, n° 9, p. 3477-82. https://archive-ouverte.unige.ch/unige:30607

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Deposited on : 2013-10-23

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