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Synchronized mechanical ventilation using electrical activity of the diaphragm in neonates

Stein, Howard
Firestone, Kimberly
Published in Clinics in Perinatology. 2012, vol. 39, no. 3, p. 525-42
Abstract The electrical activity of the diaphragm (Edi) is measured by a specialized nasogastric/orogastric tube positioned in the esophagus at the level of the crural diaphragm. Neurally adjusted ventilatory assist (NAVA) uses the Edi signal as a neural trigger and intrabreath controller to synchronize mechanical ventilatory breaths with the patient's respiratory drive and to proportionally support the patient's respiratory efforts on a breath-by-breath basis. NAVA improves patient-ventilator interaction and synchrony even in the presence of large air leaks, and might therefore be an optimal option for noninvasive ventilation in neonates.
Keywords Diaphragm/innervationElectromyographyHumansInfant, NewbornInteractive Ventilatory Support/methodsIntubation, GastrointestinalRespiratory Distress Syndrome, Newborn/therapyRespiratory Mechanics
PMID: 22954267
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Research group Maladies pulmonaires aigues et pathologies cardiaques congénitales (697)
(ISO format)
STEIN, Howard, FIRESTONE, Kimberly, RIMENSBERGER, Peter. Synchronized mechanical ventilation using electrical activity of the diaphragm in neonates. In: Clinics in Perinatology, 2012, vol. 39, n° 3, p. 525-42. doi: 10.1016/j.clp.2012.06.004 https://archive-ouverte.unige.ch/unige:30587

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Deposited on : 2013-10-23

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