Scientific article
English

Consistency of genome-based methods in measuring Metazoan evolution

Published inFEBS letters, vol. 579, no. 15, p. 3355-3361
Publication date2005
Abstract

Seven distinct genome-wide divergence measures were applied pairwise to the nine sequenced animal genomes of human, mouse, rat, chicken, pufferfish, fruit fly, mosquito, and two nematode worms (Caenorhabditis briggsae and Caenorhabditis elegans). Qualitatively, all of these divergence measures are found to correlate with the estimated time since speciation; however, marked deviations are observed in a few lineages. The distinct genome divergence measures also correlate well among themselves, indicating that most of the processes shaping genomes are dominated by neutral events. The deviations from the clock-like scenario in some lineages are observed consistently by several measures, implicitly confirming their reliability.

Keywords
  • Animals
  • Evolution, Molecular
  • Genome
  • Genomics/methods
  • Humans
  • Mutation/genetics
  • Time Factors
Affiliation entities Not a UNIGE publication
Citation (ISO format)
ZDOBNOV, Evgeny et al. Consistency of genome-based methods in measuring Metazoan evolution. In: FEBS letters, 2005, vol. 579, n° 15, p. 3355–3361. doi: 10.1016/j.febslet.2005.04.006
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Article (Published version)
accessLevelRestricted
Identifiers
Journal ISSN0014-5793
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