Scientific article

The ecoresponsive genome of Daphnia pulex

ContributorsColbourne, John K
Published inScience, vol. 331, no. 6017, p. 555-561
Publication date2011

We describe the draft genome of the microcrustacean Daphnia pulex, which is only 200 megabases and contains at least 30,907 genes. The high gene count is a consequence of an elevated rate of gene duplication resulting in tandem gene clusters. More than a third of Daphnia's genes have no detectable homologs in any other available proteome, and the most amplified gene families are specific to the Daphnia lineage. The coexpansion of gene families interacting within metabolic pathways suggests that the maintenance of duplicated genes is not random, and the analysis of gene expression under different environmental conditions reveals that numerous paralogs acquire divergent expression patterns soon after duplication. Daphnia-specific genes, including many additional loci within sequenced regions that are otherwise devoid of annotations, are the most responsive genes to ecological challenges.

  • Adaptation, Physiological
  • Amino Acid Sequence
  • Animals
  • Base Sequence
  • Chromosome Mapping
  • Daphnia/genetics/physiology
  • Ecosystem
  • Environment
  • Evolution, Molecular
  • Gene Conversion
  • Gene Duplication
  • Gene Expression
  • Gene Expression Profiling
  • Gene Expression Regulation
  • Genes
  • Genes, Duplicate
  • Genome
  • Metabolic Networks and Pathways/genetics
  • Molecular Sequence Annotation
  • Molecular Sequence Data
  • Multigene Family
  • Phylogeny
  • Sequence Analysis, DNA
Citation (ISO format)
COLBOURNE, John K. The ecoresponsive genome of Daphnia pulex. In: Science, 2011, vol. 331, n° 6017, p. 555–561. doi: 10.1126/science.1197761
Main files (1)
Article (Published version)
ISSN of the journal0036-8075

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