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Title

The ecoresponsive genome of Daphnia pulex

Authors
Colbourne, John K
Pfrender, Michael E
Gilbert, Donald
Thomas, W Kelley
Tucker, Abraham
Oakley, Todd H
Tokishita, Shinichi
Aerts, Andrea
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Published in Science. 2011, vol. 331, no. 6017, p. 555-61
Abstract We describe the draft genome of the microcrustacean Daphnia pulex, which is only 200 megabases and contains at least 30,907 genes. The high gene count is a consequence of an elevated rate of gene duplication resulting in tandem gene clusters. More than a third of Daphnia's genes have no detectable homologs in any other available proteome, and the most amplified gene families are specific to the Daphnia lineage. The coexpansion of gene families interacting within metabolic pathways suggests that the maintenance of duplicated genes is not random, and the analysis of gene expression under different environmental conditions reveals that numerous paralogs acquire divergent expression patterns soon after duplication. Daphnia-specific genes, including many additional loci within sequenced regions that are otherwise devoid of annotations, are the most responsive genes to ecological challenges.
Keywords Adaptation, PhysiologicalAmino Acid SequenceAnimalsBase SequenceChromosome MappingDaphnia/genetics/physiologyEcosystemEnvironmentEvolution, MolecularGene ConversionGene DuplicationGene ExpressionGene Expression ProfilingGene Expression RegulationGenesGenes, DuplicateGenomeMetabolic Networks and Pathways/geneticsMolecular Sequence AnnotationMolecular Sequence DataMultigene FamilyPhylogenySequence Analysis, DNA
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PMID: 21292972
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Research group Génomique Evolutionnaire Computationnelle (830)
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COLBOURNE, John K et al. The ecoresponsive genome of Daphnia pulex. In: Science, 2011, vol. 331, n° 6017, p. 555-61. https://archive-ouverte.unige.ch/unige:30559

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Deposited on : 2013-10-22

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