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Title

The InterPro database, an integrated documentation resource for protein families, domains and functional sites

Authors
Apweiler, Rolf
Attwood, Teresa K
Bateman, Alex
Birney, Ewan
Biswas, Margaret
Bucher, Philipp
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Published in Nucleic Acids Research. 2001, vol. 29, no. 1, p. 37-40
Abstract Signature databases are vital tools for identifying distant relationships in novel sequences and hence for inferring protein function. InterPro is an integrated documentation resource for protein families, domains and functional sites, which amalgamates the efforts of the PROSITE, PRINTS, Pfam and ProDom database projects. Each InterPro entry includes a functional description, annotation, literature references and links back to the relevant member database(s). Release 2.0 of InterPro (October 2000) contains over 3000 entries, representing families, domains, repeats and sites of post-translational modification encoded by a total of 6804 different regular expressions, profiles, fingerprints and Hidden Markov Models. Each InterPro entry lists all the matches against SWISS-PROT and TrEMBL (more than 1,000,000 hits from 462,500 proteins in SWISS-PROT and TrEMBL). The database is accessible for text- and sequence-based searches at http://www.ebi.ac.uk/interpro/. Questions can be emailed to interhelp@ebi.ac.uk.
Keywords Databases, FactualInformation ServicesInternetProtein Structure, TertiaryProteins/chemistry/genetics
Identifiers
PMID: 11125043
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Structures
Research group Calipho (80)
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APWEILER, Rolf et al. The InterPro database, an integrated documentation resource for protein families, domains and functional sites. In: Nucleic Acids Research, 2001, vol. 29, n° 1, p. 37-40. https://archive-ouverte.unige.ch/unige:30556

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Deposited on : 2013-10-22

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