Ethanol metabolite acetic acid as causative agent for type-1 hypersensitivity-like reactions to alcoholic beverages

Boehncke, Wolf-Henning; Gall, H.

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Title		Ethanol metabolite acetic acid as causative agent for type-1 hypersensitivity-like reactions to alcoholic beverages
Authors		Boehncke, Wolf-Henning Gall, H.
Published in		Clinical and Experimental Allergy. 1996, vol. 26, no. 9, p. 1089-1091
Abstract		BACKGROUND: Adverse reactions to alcoholic beverages are common and more frequently mediated by immunological mechanisms than previously thought. OBJECTIVE: To elucidate relevant allergens in this context we studied patients with an informative medical history. METHODS: This report describes a comprehensive allergological approach in a patient exhibiting type-I hypersensitivity-like reactions towards beverages and medication containing alcohol, and salad dressings with acetic acid. RESULTS: The ethanol metabolite acetic acid was found to yield positive prick test results in concentrations not eliciting reactions in healthy and atopic controls. CONCLUSIONS: Among other ethanol metabolites, acetic acid is a potential allergen in the context of hypersensitivity towards alcoholic beverages.
Keywords		Acetic Acid/adverse effects/metabolism — Aged — Allergens/adverse effects — Angioedema/etiology — Conjunctivitis, Allergic/etiology — Ethanol/adverse effects/metabolism — Female — Humans — Hypersensitivity, Immediate/*etiology — Skin Tests — Urticaria/etiology
Identifiers		DOI: 10.1046/j.1365-2222.1996.d01-410.x PMID: 8889265
Full text		Article - Limited access to UNIGE Other version: http://onlinelibrary.wiley.com/store/10.1111/j.1365-2222.1996.tb00648.x/asset/j.1365-2222.1996.tb00648.x.pdf?v=1&t=hk...
Citation (ISO format)		BOEHNCKE, Wolf-Henning, GALL, H. Ethanol metabolite acetic acid as causative agent for type-1 hypersensitivity-like reactions to alcoholic beverages. In: Clinical and Experimental Allergy, 1996, vol. 26, n° 9, p. 1089-1091. https://archive-ouverte.unige.ch/unige:29760

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Ethanol metabolite acetic acid as causative agent for type-1 hypersensitivity-like reactions to alcoholic beverages