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Scientific article
English

Psoriasis and bacterial superantigens--formal or causal correlation?

Published inTrends in microbiology, vol. 4, no. 12, p. 485-489
Publication date1996
Abstract

Superantigens have recently been identified as candidates for triggering crucial events in the development of psoriasis. Seemingly contradictory observations may complement each other when discussed in the context of the concept of an effector cell cascade initiated by bacterial superantigens that eventually brings about disruption of peripheral tolerance of a CD8+ T-cell subset.

Keywords
  • Alleles
  • Animals
  • Antigens, Bacterial/*immunology/physiology
  • CD8-Positive T-Lymphocytes/immunology
  • Exotoxins/physiology
  • Histocompatibility Antigens Class I/immunology
  • Histocompatibility Antigens Class II/genetics/immunology
  • Humans
  • Intercellular Adhesion Molecule-1/physiology
  • Mice
  • Mice, SCID
  • Psoriasis/*etiology/immunology/microbiology
  • Receptors, Antigen, T-Cell, alpha-beta/physiology
  • Skin/immunology
  • Skin Transplantation
  • Streptococcus/chemistry
  • Superantigens/*immunology
  • T-Lymphocyte Subsets/immunology
Affiliation Not a UNIGE publication
Citation (ISO format)
BOEHNCKE, Wolf-Henning. Psoriasis and bacterial superantigens--formal or causal correlation? In: Trends in microbiology, 1996, vol. 4, n° 12, p. 485–489. doi: 10.1016/s0966-842x(97)82910-1
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ISSN of the journal0966-842X
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