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Psoriasis im Tiermodell

Published in Der Hautarzt. 1997, vol. 48, no. 10, p. 707-713
Abstract Co-existing inflammation and epidermal hyperproliferation characteristic for psoriasis have been shown to be reproducible in several animal models utilizing a variety of different strategies. These models highlight some points of the multicausal pathogenesis of psoriasis. Based on observations made in the animal models, a hypothesis is proposed for the pathogenesis of psoriasis, the elements of which can be tested in a recently established xenogeneic transplantation model.
Keywords Animals*Disease Models, AnimalHLA-B27 Antigen/geneticsHumansMiceMice, SCIDMice, TransgenicPsoriasis/*etiology/genetics/pathologySkin/pathologyTransplantation, Heterologous
PMID: 9441162
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BOEHNCKE, Wolf-Henning. Psoriasis im Tiermodell. In: Der Hautarzt, 1997, vol. 48, n° 10, p. 707-713.

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Deposited on : 2013-09-20

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