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Scientific article
English

Die photodynamische Therapie an der Schwelle zur klinischen Anwendung bei disseminierten Dermatosen

Other titlePhotodynamic therapy at the threshold of clinical use in disseminated dermatoses
Published inDer Hautarzt, vol. 47, no. 11, p. 825-831
Publication date1996
Abstract

Photodynamic therapy (PDT) involving the sequential administration of photosensitizing drugs and light has a successful record in the treatment of superficial tumors. Recent investigations document not only cytotoxicity but also immunomodulatory effects of PDT. Cell type as well as state of activation and differentiation are among the parameters influencing susceptibility to PDT, thus allowing targeting of selected cell (sub-)populations. In addition to lasers, non-coherent light sources are also effective. These features, along with current clinical experience, suggest PDT as an interesting alternative to better established photochemotherapies in the treatment of widespread malignant and benign dermatoses.

Keywords
  • Humans
  • Lymphoma, T-Cell, Cutaneous/drug therapy/pathology
  • Photochemotherapy/*methods
  • Psoriasis/drug therapy/pathology
  • Skin/pathology
  • Skin Diseases/*drug therapy/pathology
  • Skin Neoplasms/*drug therapy/pathology
  • Treatment Outcome
Affiliation Not a UNIGE publication
Citation (ISO format)
BOEHNCKE, Wolf-Henning, KAUFMANN, Roland. Die photodynamische Therapie an der Schwelle zur klinischen Anwendung bei disseminierten Dermatosen. In: Der Hautarzt, 1996, vol. 47, n° 11, p. 825–831. doi: 10.1007/s001050050515
Identifiers
ISSN of the journal0017-8470
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