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Renal carcinoma relapse presenting as a peripheral nerve sheath tumor: A case report and brief review of the literature

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Published in Neurochirurgie. 2013, vol. 59, no. 3, p. 128-32
Abstract We report a rare case of renal carcinoma metastasis involving a lumbar nerve root. Metastases to nerve roots are rare occurrences, and to our knowledge, only six cases have been reported so far in the literature. The patient in this report presented with weakness in the right lower limb and intractable pain irradiating along the L5 dermatome. MRI findings revealed a right-sided L5 nerve root mass, suggestive of a schwannoma, involving the spinal ganglion and its extraforaminal region. Complete macroscopic resection of this mass was performed, and histopathologic analysis confirmed the lesion to be a metastasis of a renal clear cell carcinoma. Local radiotherapy was given and tyrosine kinase inhibitors administered. At 5months, the patient was pain-free and his right limb weakness had completely resolved. A tumoral recurrence could be observed on the control MRI 5months after surgery. This report presents the first case of a patient with a renal clear cell carcinoma metastasis to a L5 nerve root, as well as a brief review of previous cases of metastases to peripheral nerve roots.
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PMID: 23806763
Note Rechute de carcinome rénal sous la forme d'une tumeur des gaines nerveuses périphériques: cas clinique et brève revue de la littérature
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Research group Groupe Schaller Karl Lothard (neurochirurgie) (851)
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CABRILO, Ivan et al. Renal carcinoma relapse presenting as a peripheral nerve sheath tumor: A case report and brief review of the literature. In: Neurochirurgie, 2013, vol. 59, n° 3, p. 128-32. https://archive-ouverte.unige.ch/unige:29465

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Deposited on : 2013-08-28

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