en
Scientific article
English

Tooth eruption: altered gene expression in the dental follicle of patients with cleidocranial dysplasia

Published inOrthodontics & craniofacial research, vol. 16, no. 1, p. 20-27
Publication date2013
Abstract

The dental follicle plays an important role in tooth eruption by providing key regulators of osteogenesis and bone resorption. Patients with cleidocranial dysplasia (CCD) exhibit delayed tooth eruption in combination with increased bone density in the maxilla and mandible, suggesting disturbances in bone remodeling. The aim of this study was to determine the expression of genes relevant for tooth eruption and bone remodeling in the dental follicles of patients with CCD and normal subjects.

Keywords
  • Adolescent
  • Adult
  • Bone Remodeling/genetics
  • Case-Control Studies
  • Cleidocranial Dysplasia/genetics/physiopathology
  • Dental Sac/metabolism
  • Female
  • Gene Expression
  • Humans
  • Macrophage Colony-Stimulating Factor/genetics
  • Male
  • Osteoprotegerin/genetics
  • RANK Ligand/genetics
  • Receptor Activator of Nuclear Factor-kappa B/genetics
  • Statistics, Nonparametric
  • Tooth Eruption/genetics
  • Young Adult
Citation (ISO format)
DOROTHEOU, Domna et al. Tooth eruption: altered gene expression in the dental follicle of patients with cleidocranial dysplasia. In: Orthodontics & craniofacial research, 2013, vol. 16, n° 1, p. 20–27. doi: 10.1111/ocr.12000
Main files (1)
Article (Published version)
accessLevelRestricted
Identifiers
ISSN of the journal1601-6335
550views
1downloads

Technical informations

Creation08/07/2013 1:41:00 PM
First validation08/07/2013 1:41:00 PM
Update time03/14/2023 8:22:15 PM
Status update03/14/2023 8:22:15 PM
Last indexation01/16/2024 2:00:42 AM
All rights reserved by Archive ouverte UNIGE and the University of GenevaunigeBlack