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Title

Tooth eruption: altered gene expression in the dental follicle of patients with cleidocranial dysplasia

Authors
Gkantidis, N
Karamolegkou, M
Kalyvas, D
Kitraki, E
Published in Orthodontics and Craniofacial Research. 2013, vol. 16, no. 1, p. 20-7
Abstract The dental follicle plays an important role in tooth eruption by providing key regulators of osteogenesis and bone resorption. Patients with cleidocranial dysplasia (CCD) exhibit delayed tooth eruption in combination with increased bone density in the maxilla and mandible, suggesting disturbances in bone remodeling. The aim of this study was to determine the expression of genes relevant for tooth eruption and bone remodeling in the dental follicles of patients with CCD and normal subjects.
Keywords AdolescentAdultBone Remodeling/geneticsCase-Control StudiesCleidocranial Dysplasia/genetics/physiopathologyDental Sac/metabolismFemaleGene ExpressionHumansMacrophage Colony-Stimulating Factor/geneticsMaleOsteoprotegerin/geneticsRANK Ligand/geneticsReceptor Activator of Nuclear Factor-kappa B/geneticsStatistics, NonparametricTooth Eruption/geneticsYoung Adult
Identifiers
PMID: 23311656
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Structures
Research group Groupe Kiliaridis Stavros (médecine dentaire) (239)
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(ISO format)
DOROTHEOU, Domna et al. Tooth eruption: altered gene expression in the dental follicle of patients with cleidocranial dysplasia. In: Orthodontics and Craniofacial Research, 2013, vol. 16, n° 1, p. 20-7. https://archive-ouverte.unige.ch/unige:29207

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Deposited on : 2013-08-12

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