en
Scientific article
English

Cortical folding in Broca's area relates to obstetric complications in schizophrenia patients and healthy controls

Published inPsychological medicine, vol. 42, no. 6, p. 1329-1337
Publication date2012
Abstract

The increased occurrence of obstetric complications (OCs) in patients with schizophrenia suggests that alterations in neurodevelopment may be of importance to the aetiology of the illness. Abnormal cortical folding may reflect subtle deviation from normal neurodevelopment during the foetal or neonatal period. In the present study, we hypothesized that OCs would be related to cortical folding abnormalities in schizophrenia patients corresponding to areas where patients with schizophrenia display altered cortical folding when compared with healthy controls.

Keywords
  • Adult
  • Algorithms
  • Animals
  • Case-Control Studies
  • Female
  • Fetal Development/physiology
  • Frontal Lobe/abnormalities/embryology
  • Functional Laterality
  • Humans
  • Image Processing, Computer-Assisted
  • Linear Models
  • Magnetic Resonance Imaging/methods
  • Male
  • Middle Aged
  • Obstetric Labor Complications/epidemiology/pathology
  • Pregnancy
  • Prevalence
  • Schizophrenia/epidemiology/pathology
Citation (ISO format)
HAUKVIK, U K et al. Cortical folding in Broca’s area relates to obstetric complications in schizophrenia patients and healthy controls. In: Psychological medicine, 2012, vol. 42, n° 6, p. 1329–1337. doi: 10.1017/S0033291711002315
Main files (1)
Article (Published version)
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Identifiers
ISSN of the journal0033-2917
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