Islet endothelial activation and oxidative stress gene expression is reduced by IL-1Ra treatment in the type 2 diabetic GK rat
Contributeurs/tricesLacraz, Grégory; Giroix, Marie-Hélène; Kassis, Nadim; Coulaud, Josiane; Galinier, Anne; Noll, Christophe; Cornut Matthey-Doret, Mélanie; Schmidlin, Fabien; Paul, Jean-Louis; Janel, Nathalie; Irminger, Jean-Claude; Kergoat, Micheline; Portha, Bernard; Donath, Marc Y; Ehses, Jan A; Homo-Delarche, Françoise
Publié dansPloS one, vol. 4, no. 9, e6963
Date de publication2009
Résumé
Mots-clés
- Animals
- Antioxidants/metabolism
- Diabetes Mellitus, Experimental/metabolism
- Diabetes Mellitus, Type 2/metabolism
- Endothelial Cells/cytology
- Gene Expression Regulation
- Inflammation
- Interleukin 1 Receptor Antagonist Protein/metabolism
- Interleukin-1/metabolism
- Islets of Langerhans/cytology
- Male
- Models, Biological
- Oxidative Stress
- Rats
- Rats, Wistar
Structure d'affiliation
Groupe de recherche
Citation (format ISO)
LACRAZ, Grégory et al. Islet endothelial activation and oxidative stress gene expression is reduced by IL-1Ra treatment in the type 2 diabetic GK rat. In: PloS one, 2009, vol. 4, n° 9, p. e6963. doi: 10.1371/journal.pone.0006963
Fichiers principaux (1)
Article (Published version)
Identifiants
- PID : unige:28881
- DOI : 10.1371/journal.pone.0006963
- PMID : 19742300
ISSN du journal1932-6203