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Title

Bronchopneumopathie chronique obstructive: risques et bénéfices d'un traitement de testostérone
Authors
Samaras, N
Samaras, Dimitrios
Lang, P-O
Bridevaux, Pierre-Olivier
Gex, Grégoire
Janssens, Jean-Paul
Pichard, Claude
Published in Revue médicale suisse. 2012, vol. 8, no. 363, p. 2224-2227
Abstract Muscular wasting is frequently encountered in COPD patients and is related to a decrease in exercise tolerance, a higher morbidity and mortality. One of the potential causes isa low serum testosterone, which is frequent in COPD. Various studies have explored the effect of testosterone administration alone or as part of combined pulmonary rehabilitation and nutrition protocols. Testosterone had a positive impact on muscle mass and force, and to a lesser extent on physical endurance and respiratory parameters. Future studies should better define appropriate dosage and treatment duration. In the meantime, testosterone should be administered to COPD patients with overt hypogonadism, or in multidisciplinary specialized programmes.
Keywords Androgens/adverse effects/blood/therapeutic use — Exercise Tolerance — Humans — Muscular Atrophy/drug therapy/etiology — Physical Endurance/drug effects — Pulmonary Disease, Chronic Obstructive/drug therapy/physiopathology — Testosterone/adverse effects/blood/therapeutic use
Identifiers
PMID: 23240298
Full text
Article (Published version) (549 Kb) - document accessible for UNIGE members only Limited access to UNIGE
Other version: http://rms.medhyg.ch/numero-363-page-2224.htm
Structures
Faculté de médecine / Section de médecine clinique / Département de médecine
Research group Nutrition clinique (597)
Citation
(ISO format) 		SAMARAS, N et al. Bronchopneumopathie chronique obstructive: risques et bénéfices d'un traitement de testostérone. In: Revue médicale suisse, 2012, vol. 8, n° 363, p. 2224-2227. https://archive-ouverte.unige.ch/unige:28871

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Deposited on : 2013-07-10

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