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Title

Bronchopneumopathie chronique obstructive: risques et bénéfices d’un traitement de testostérone

Authors
Samaras, N
Lang, P-O
Bridevaux, P-O
Janssens, J-P
Published in Revue médicale suisse. 2012, vol. 8, no. 363, p. 2224-2227
Abstract Muscular wasting is frequently encountered in COPD patients and is related to a decrease in exercise tolerance, a higher morbidity and mortality. One of the potential causes isa low serum testosterone, which is frequent in COPD. Various studies have explored the effect of testosterone administration alone or as part of combined pulmonary rehabilitation and nutrition protocols. Testosterone had a positive impact on muscle mass and force, and to a lesser extent on physical endurance and respiratory parameters. Future studies should better define appropriate dosage and treatment duration. In the meantime, testosterone should be administered to COPD patients with overt hypogonadism, or in multidisciplinary specialized programmes.
Keywords Androgens/adverse effects/blood/therapeutic useExercise ToleranceHumansMuscular Atrophy/drug therapy/etiologyPhysical Endurance/drug effectsPulmonary Disease, Chronic Obstructive/drug therapy/physiopathologyTestosterone/adverse effects/blood/therapeutic use
Identifiers
PMID: 23240298
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Other version: http://rms.medhyg.ch/numero-363-page-2224.htm
Structures
Research group Nutrition clinique (597)
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(ISO format)
SAMARAS, N et al. Bronchopneumopathie chronique obstructive: risques et bénéfices d’un traitement de testostérone. In: Revue médicale suisse, 2012, vol. 8, n° 363, p. 2224-2227. https://archive-ouverte.unige.ch/unige:28871

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Deposited on : 2013-07-10

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