Effects of ovariectomy on the changes in microarchitecture and material level properties in response to hind leg disuse in female rats

Maimoun, Laurent; Brennan-Speranza, Tara C.; Rizzoli, René; Ammann, Patrick

doi:10.1016/j.bone.2012.05.001

Scientific article

English

Effects of ovariectomy on the changes in microarchitecture and material level properties in response to hind leg disuse in female rats

ContributorsMaimoun, Laurent; Brennan-Speranza, Tara C.; Rizzoli, René; Ammann, Patrick

Published inBone, vol. 51, no. 3, p. 586-591

Publication date2012

Abstract

Ovariectomy (OVX) and immobilization are known to decrease bone mineral density and alter its microarchitecture. Their effects on the material level properties of bone, a determinant of bone strength, are still largely unknown. We investigated the effect of OVX and/or disuse achieved by sciatic neurectomy (NX) in 6-month-old Sprague Dawley female rats.

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Citation (ISO format)

MAIMOUN, Laurent et al. Effects of ovariectomy on the changes in microarchitecture and material level properties in response to hind leg disuse in female rats. In: Bone, 2012, vol. 51, n° 3, p. 586–591. doi: 10.1016/j.bone.2012.05.001

Article (Published version)

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PID : unige:28830
DOI : 10.1016/j.bone.2012.05.001

Journal ISSN1873-2763

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Effects of ovariectomy on the changes in microarchitecture and material level properties in response to hind leg disuse in female rats

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