Scientific article
OA Policy
English

Effects of strontium ranelate and alendronate on bone microstructure in women with osteoporosis. Results of a 2-year study

Published inOsteoporosis international, vol. 23, no. 1, p. 305-315
Collection
  • Open Access - Licence nationale Springer
Publication date2012
Abstract

Strontium ranelate appears to influence more than alendronate distal tibia bone microstructure as assessed by high-resolution peripheral quantitative computed tomography (HR-pQCT), and biomechanically relevant parameters as assessed by micro-finite element analysis (μFEA), over 2 years, in postmenopausal osteoporotic women.

Keywords
  • Aged
  • Alendronate/pharmacology/therapeutic use
  • Bone Density/drug effects
  • Bone Density Conservation Agents/pharmacology/therapeutic use
  • Bone and Bones/drug effects/pathology/radiography
  • Double-Blind Method
  • Female
  • Femur Neck/physiopathology
  • Finite Element Analysis
  • Humans
  • Lumbar Vertebrae/physiopathology
  • Middle Aged
  • Organometallic Compounds/pharmacology/therapeutic use
  • Osteoporosis, Postmenopausal/drug therapy/pathology/physiopathology/radiography
  • Radius/drug effects/pathology/radiography
  • Thiophenes/pharmacology/therapeutic use
  • Tibia/drug effects/pathology/radiography
  • Tomography, X-Ray Computed
Research groups
Citation (ISO format)
RIZZOLI, René et al. Effects of strontium ranelate and alendronate on bone microstructure in women with osteoporosis. Results of a 2-year study. In: Osteoporosis international, 2012, vol. 23, n° 1, p. 305–315. doi: 10.1007/s00198-011-1758-z
Main files (1)
Article (Published version)
accessLevelPublic
Identifiers
Journal ISSN0937-941X
518views
283downloads

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