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Un complexe moléculaire unique à l'origine de la motilité et de l'invasion des Apicomplexes

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Published in Medecine Sciences. 2013, vol. 29, no. 5, p. 515-22
Abstract Protozoan parasites belonging to the phylum Apicomplexa are of considerable medical and veterinary significance. These obligate intracellular parasites use a unique form of locomotion to traverse biological barriers and actively invade in and egress from host cells. An actin-myosin-based complex named "glideosome" drives this unusual substrate-dependent motility, which is essential for the establishment of the infection. The mechanisms involved in motility, invasion and egress are conserved throughout the phylum. This article describes the current knowledge on the invasion process of two experimentally tractable apicomplexan parasites: Toxoplasma gondii and Plasmodium falciparum.
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PMID: 23732101
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Article (Published version) (902 Kb) - public document Free access
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Research group Biologie d'un parasite intracellulaire obligatoire (773)
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FRENAL, Karine, SOLDATI-FAVRE, Dominique. Un complexe moléculaire unique à l'origine de la motilité et de l'invasion des Apicomplexes. In: Médecine/Sciences, 2013, vol. 29, n° 5, p. 515-22. https://archive-ouverte.unige.ch/unige:28788

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Deposited on : 2013-07-05

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