Chronic osteomyelitis

Uckay, Ilker; Jugun, Kheeldass; Gamulin, Axel Dorian G.; Wagener, Joe; Hoffmeyer, Pierre; Lew, Daniel Pablo

doi:10.1007/s11908-012-0286-0

Scientific article

English

Chronic osteomyelitis

Contributors

Uckay, Ilker; Jugun, Kheeldass; Gamulin, Axel Dorian G.; Wagener, Joe; Hoffmeyer, Pierre; Lew, Daniel Pablo

Published in

Current infectious disease reports, vol. 14, no. 5, p. 566-575

Collection

Open Access - Licence nationale Springer

Publication date

2012

Abstract

Chronic osteomyelitis is a multifaceted bacterial infection with common features. It absolutely requires surgery for remission. The duration and form of concomitant administration of antibiotic agents for adult patients is still based on expert opinion. The traditional recommendation of 6-12 weeks of antibiotic therapy, where, for at least the first 2-6 weeks, antibiotics should be administered intravenously, is more and more challenged in favor of an oral antibiotic treatment with selected agents from the start. There is no evidence that the total duration of antibiotic therapy for more than 4-6 weeks improves outcome, when compared with shorter regimens. Hopefully, the future will show randomized trials in the adult population, allowing optimal timing of surgical and medical therapy and sparing of unnecessary prescription, with concomitant development of antibiotic resistance. External advice from an expert team with combined surgeons and infectious disease physicians may help to reduce antibiotic consumption in a cost-effective way.

UNIGE affiliation entities

UNIGE research groups

Citation (ISO format)

UCKAY, Ilker et al. Chronic osteomyelitis. In: Current infectious disease reports, 2012, vol. 14, n° 5, p. 566–575. doi: 10.1007/s11908-012-0286-0

Article (Published version)

Identifiers

PID : unige:28748
DOI : 10.1007/s11908-012-0286-0
PMID : 22843508

Journal ISSN

1523-3847

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Creation

03/06/2013 12:52:00

First validation

03/06/2013 12:52:00

Update

14/03/2023 20:19:35

Status update

14/03/2023 20:19:34

Last indexation

30/10/2024 09:43:37

Chronic osteomyelitis

Contributors

Published in

Collection

Publication date

Abstract

UNIGE affiliation entities

UNIGE research groups

Citation (ISO format)

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Technical informations

Creation

First validation

Update

Status update

Last indexation