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Title

Nonactivated versus thrombin-activated platelets on wound healing and fibroblast-to-myofibroblast differentiation in vivo and in vitro

Authors
Heit, Yvonne
Published in Plastic and Reconstructive Surgery. 2012, vol. 129, no. 1, p. 46e-54e
Abstract Platelet preparations for tissue healing are usually preactivated before application to deliver concentrated growth factors. In this study, the authors investigated the differences between nonactivated and thrombin-activated platelets in wound healing.
Keywords AnimalsCell DifferentiationCell Movement/physiologyDiabetes Mellitus, Experimental/physiopathologyFibroblasts/physiologyImmunohistochemistryMaleMiceMice, Inbred C57BLMyofibroblasts/physiologyNeovascularization, PhysiologicPlatelet Activation/physiologyPlatelet-Rich Plasma/physiologyThrombin/metabolismTissue Therapy/methodsWound Healing/physiology
Identifiers
PMID: 22186584
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Structures
Research group Groupe Pittet Cuenod Brigitte (chirurgie plastique et reconstructive) (96)
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SCHERER-PIETRAMAGGIORI, Sandra et al. Nonactivated versus thrombin-activated platelets on wound healing and fibroblast-to-myofibroblast differentiation in vivo and in vitro. In: Plastic and Reconstructive Surgery, 2012, vol. 129, n° 1, p. 46e-54e. https://archive-ouverte.unige.ch/unige:28733

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Deposited on : 2013-06-28

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