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Title

Nonactivated versus thrombin-activated platelets on wound healing and fibroblast-to-myofibroblast differentiation in vivo and in vitro
Authors
Scherer-pietramaggiori, Sandra
Tobalem, Mickael
Vigato, Enrico
Heit, Yvonne
Modarressi Ghavami, Seyed Ali
Hinz, Boris
Pittet Cuenod, Brigitte Maud
Pietramaggiori, Giorgio
Published in Plastic and Reconstructive Surgery. 2012, vol. 129, no. 1, p. 46e-54e
Abstract Platelet preparations for tissue healing are usually preactivated before application to deliver concentrated growth factors. In this study, the authors investigated the differences between nonactivated and thrombin-activated platelets in wound healing.
Keywords Animals — Cell Differentiation — Cell Movement/physiology — Diabetes Mellitus, Experimental/physiopathology — Fibroblasts/physiology — Immunohistochemistry — Male — Mice — Mice, Inbred C57BL — Myofibroblasts/physiology — Neovascularization, Physiologic — Platelet Activation/physiology — Platelet-Rich Plasma/physiology — Thrombin/metabolism — Tissue Therapy/methods — Wound Healing/physiology
Identifiers
PMID: 22186584
Full text
Article (Published version) (770 Kb) - document accessible for UNIGE members only Limited access to UNIGE
Structures
Faculté de médecine / Section de médecine clinique / Département de chirurgie
Research group Groupe Pittet Cuenod Brigitte (chirurgie plastique et reconstructive) (96)
Citation
(ISO format) 		SCHERER-PIETRAMAGGIORI, Sandra et al. Nonactivated versus thrombin-activated platelets on wound healing and fibroblast-to-myofibroblast differentiation in vivo and in vitro. In: Plastic and Reconstructive Surgery, 2012, vol. 129, n° 1, p. 46e-54e. doi: 10.1097/PRS.0b013e3182362010 https://archive-ouverte.unige.ch/unige:28733

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Deposited on : 2013-06-28

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