en
Scientific article
English

Nonactivated versus thrombin-activated platelets on wound healing and fibroblast-to-myofibroblast differentiation in vivo and in vitro

Published inPlastic and reconstructive surgery, vol. 129, no. 1, p. 46e-54e
Publication date2012
Abstract

Platelet preparations for tissue healing are usually preactivated before application to deliver concentrated growth factors. In this study, the authors investigated the differences between nonactivated and thrombin-activated platelets in wound healing.

Keywords
  • Animals
  • Cell Differentiation
  • Cell Movement/physiology
  • Diabetes Mellitus, Experimental/physiopathology
  • Fibroblasts/physiology
  • Immunohistochemistry
  • Male
  • Mice
  • Mice, Inbred C57BL
  • Myofibroblasts/physiology
  • Neovascularization, Physiologic
  • Platelet Activation/physiology
  • Platelet-Rich Plasma/physiology
  • Thrombin/metabolism
  • Tissue Therapy/methods
  • Wound Healing/physiology
Citation (ISO format)
SCHERER-PIETRAMAGGIORI, Sandra et al. Nonactivated versus thrombin-activated platelets on wound healing and fibroblast-to-myofibroblast differentiation in vivo and in vitro. In: Plastic and reconstructive surgery, 2012, vol. 129, n° 1, p. 46e–54e. doi: 10.1097/PRS.0b013e3182362010
Main files (1)
Article (Published version)
accessLevelRestricted
Identifiers
ISSN of the journal0032-1052
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3downloads

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