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Nonactivated versus thrombin-activated platelets on wound healing and fibroblast-to-myofibroblast differentiation in vivo and in vitro |
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Published in | Plastic and Reconstructive Surgery. 2012, vol. 129, no. 1, p. 46e-54e | |
Abstract | Platelet preparations for tissue healing are usually preactivated before application to deliver concentrated growth factors. In this study, the authors investigated the differences between nonactivated and thrombin-activated platelets in wound healing. | |
Keywords | Animals — Cell Differentiation — Cell Movement/physiology — Diabetes Mellitus, Experimental/physiopathology — Fibroblasts/physiology — Immunohistochemistry — Male — Mice — Mice, Inbred C57BL — Myofibroblasts/physiology — Neovascularization, Physiologic — Platelet Activation/physiology — Platelet-Rich Plasma/physiology — Thrombin/metabolism — Tissue Therapy/methods — Wound Healing/physiology | |
Identifiers | PMID: 22186584 | |
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Research group | Groupe Pittet Cuenod Brigitte (chirurgie plastique et reconstructive) (96) | |
Citation (ISO format) | SCHERER-PIETRAMAGGIORI, Sandra et al. Nonactivated versus thrombin-activated platelets on wound healing and fibroblast-to-myofibroblast differentiation in vivo and in vitro. In: Plastic and Reconstructive Surgery, 2012, vol. 129, n° 1, p. 46e-54e. doi: 10.1097/PRS.0b013e3182362010 https://archive-ouverte.unige.ch/unige:28733 |